Results 91 to 100 of about 103,162 (311)

Adjacent Segment Pathology in Spinal Fusion Surgery [PDF]

, 2023
Taeyup Kim, Yung Park, Jae‐Won Shin, Ji-Won Kwon, Byung Ho Lee, Si-Young Park, Joong Won Ha, Kyung‐Soo Suk, Seong-Hwan Moon, Hak‐Sun Kim   +9 more
openalex   +1 more source

Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism

Advanced Science, EarlyView.
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce, Aert F. Scheper, Aung Myat Phyo, Roisin O’ Flaherty, Richard Drake, Aiden Devitt, Martina Marchetti‐Deschmann, Radka Saldova, Abhay Pandit   +8 more
wiley   +1 more source

Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real‐Time Protection

Advanced Science, EarlyView.
BrainGuard enables real‐time and interpretable assessment of brain injury caused by brain computer interface (BCI). Using feature‐based Gaussian process (GP) emulators trained on limited biomechanical data, it efficiently predicts full‐field strain and constructs patient‐specific digital brain twins to support clinical diagnosis and long‐term BCI ...
Chufan He, Yanjun Ding, Timon Rabczuk, Chensen Ding   +3 more
wiley   +1 more source

Titanium and tantalum as mesenchymal stem cell scaffolds for spinal fusion: an in vitro comparative study [PDF]

, 2011
Juan F. Blanco, Fermín Sánchez‐Guijo, Soraya Carrancio, Sandra Muntión, Jesús G. Briñón, María-Consuelo del Cañizo   +5 more
openalex   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Novel Approach to Difficult Spinal Reconstruction: Bilateral Simultaneous Rib and Iliac Crest Vascularized Bone Graft Spinoplastic Surgery

Plastic and Reconstructive Surgery, Global Open
Summary:. Pseudoarthrosis is a severe complication of spinal fusion surgery with occurrence rates as high as 35%–40%. Current options of revision surgery to correct pseudoarthrosis frequently carry high failure rates and risk of developing junctional ...
Maria Shvedova, MD, PhD, Isra Abdulwadood, BS, Daniel M. Vernik, MS, Max A. Shrout, MD, Jonathan L. Jeger, MD, Dylon C. Buchanan, MS, Alexander Ropper, MD, Sebastian Winocour, MD, MSc, FACS, Michael Bohl, MD, Maziyar A. Kalani, MD, Edward M. Reece, MD, MBA   +10 more
doaj   +1 more source

SPINAL FUSION [PDF]

The Journal of Bone and Joint Surgery. British volume, 1953
openaire   +2 more sources

Application of Image-Fusion 3D Printing Model in Total En Bloc Spondylectomy for Spinal Malignant Tumors [PDF]

, 2022
Yushan Wang, Yi Xiang, Qiaoqiao Tian, Wei Luo, Hao Fan, Peng Ren, Zhi Lv, Jia Lv, Junjun Bai, Xiaochen Qiao, Yi Feng   +10 more
openalex   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source