Results 21 to 30 of about 99,877 (265)

Platelet-rich plasma for the spinal fusion

open access: yesJournal of Orthopaedic Surgery, 2018
There has been a wide interest in using platelet-rich plasma (PRP) as a therapeutic agent to enhance spinal fusion. There are two review articles based only on clinical studies regarding the effect of PRP on spinal fusion.
Moon Soo Park   +5 more
doaj   +1 more source

The effect of platelet-rich plasma on the fusion rate and clinical outcome of spinal fusion surgery: A systematic review and meta-analysis.

open access: yesPLoS ONE, 2020
BackgroundPlatelet-rich plasma (PRP) is widely used in many orthopedic surgeries and spinal disease treatments; however, the effect of PRP on spinal fusion remains controversial.Questions/purposesTo assess the fusion rate and clinical results of PRP ...
Ying-Feng Cai   +6 more
doaj   +1 more source

Mesenchymal Stem Cell Exosomes Enhance Posterolateral Spinal Fusion in a Rat Model

open access: yesCells
Spinal fusion, a common surgery performed for degenerative lumbar conditions, often uses recombinant human bone morphogenetic protein 2 (rhBMP-2) that is associated with adverse effects.
Wing Moon Raymond Lam   +6 more
doaj   +1 more source

Hypomagnesemia after spinal fusion [PDF]

open access: yesJornal de Pediatria, 2012
To determine the frequency of hypomagnesemia in pediatric patients after spinal fusion, to verify whether postoperative magnesium levels were lower than preoperative levels and, if so, to identify possible causes and assess the clinical repercussions for patients.This was a retrospective descriptive study of pediatric patients admitted to a pediatric ...
Larissa Rossato, Chrun   +1 more
openaire   +2 more sources

IMPACT OF THE LUMBAR STIFFNESS RELATED TO ARTHRODESIS TO FUNCTIONAL DISABILITY

open access: yesColuna/Columna, 2021
Objective: To assess the impact of stiffness associated with lumbar spinal fusion on disability and quality of life. Methods: This is a retrospective study including 40 patients (mean age: 57.7 ± 16.2) who underwent spinal surgery with fusion including ...
Camila Maribondo Medeiros Ramos   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Posterior Spinal Fusion for Severe Kyphosis in a Child with Gaucher Disease: A Case Report and Review of the Literature

open access: yesSurgeries
Background: Skeleton involvement is one of the most significant aspects of Gaucher disease (GD). However, the treatment for spinal involvement in GD among patients undergoing enzyme replacement therapy (ERT) is poorly characterized.
Tengfei Zhao   +5 more
doaj   +1 more source

Comparing Fusion Rates Between Fresh-Frozen and Freeze-Dried Allografts in Anterior Cervical Discectomy and Fusion

open access: yesWorld Neurosurgery: X, 2022
Objective: The objective of this retrospective study is to compare the fusion rates in anterior cervical discectomy and fusion surgery using freeze-dried versus fresh-frozen allografts. Methods: The study comprised 79 patients.
Derron Yu   +8 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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