Results 21 to 30 of about 100,493 (264)

The effect of platelet-rich plasma on the fusion rate and clinical outcome of spinal fusion surgery: A systematic review and meta-analysis.

open access: yesPLoS ONE, 2020
BackgroundPlatelet-rich plasma (PRP) is widely used in many orthopedic surgeries and spinal disease treatments; however, the effect of PRP on spinal fusion remains controversial.Questions/purposesTo assess the fusion rate and clinical results of PRP ...
Ying-Feng Cai   +6 more
doaj   +1 more source

Mesenchymal Stem Cell Exosomes Enhance Posterolateral Spinal Fusion in a Rat Model

open access: yesCells
Spinal fusion, a common surgery performed for degenerative lumbar conditions, often uses recombinant human bone morphogenetic protein 2 (rhBMP-2) that is associated with adverse effects.
Wing Moon Raymond Lam   +6 more
doaj   +1 more source

Hypomagnesemia after spinal fusion [PDF]

open access: yesJornal de Pediatria, 2012
To determine the frequency of hypomagnesemia in pediatric patients after spinal fusion, to verify whether postoperative magnesium levels were lower than preoperative levels and, if so, to identify possible causes and assess the clinical repercussions for patients.This was a retrospective descriptive study of pediatric patients admitted to a pediatric ...
Larissa Rossato, Chrun   +1 more
openaire   +2 more sources

IMPACT OF THE LUMBAR STIFFNESS RELATED TO ARTHRODESIS TO FUNCTIONAL DISABILITY

open access: yesColuna/Columna, 2021
Objective: To assess the impact of stiffness associated with lumbar spinal fusion on disability and quality of life. Methods: This is a retrospective study including 40 patients (mean age: 57.7 ± 16.2) who underwent spinal surgery with fusion including ...
Camila Maribondo Medeiros Ramos   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Posterior Spinal Fusion for Severe Kyphosis in a Child with Gaucher Disease: A Case Report and Review of the Literature

open access: yesSurgeries
Background: Skeleton involvement is one of the most significant aspects of Gaucher disease (GD). However, the treatment for spinal involvement in GD among patients undergoing enzyme replacement therapy (ERT) is poorly characterized.
Tengfei Zhao   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Topology Optimization of Spinal Cage Designs for Improved Stress Distribution and Bone Graft Window

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023
Interbody fusion is utilized as a treatment for spinal degenerative diseases. Spinal cages, also known as intervertebral cages or interbody fusion devices, are implants employed in spinal surgery to address these conditions and promote spinal stability ...
Meltem Eryıldız
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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