Results 61 to 70 of about 1,534,522 (405)

Comprehensive end‐to‐end dosimetry audit for stereotactic body radiotherapy in spine, lung, and soft tissue

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To create and conduct a comprehensive onsite end‐to‐end dosimetry audit to assess treatment accuracy of spine, lung, and soft tissue Stereotactic Body Radiotherapy (SBRT) across Australian and New Zealand (ANZ) radiotherapy centers. Methods The Australian Clinical Dosimetry Service (ACDS) anthropomorphic thorax phantom underwent a CT ...
Maddison Shaw   +8 more
wiley   +1 more source

IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Background Despite extensive research, there is still a need for safe and effective agents to promote spinal fusion. Interleukin (IL)-1β is an important factor which influences the bone repair and remodelling.
Zengxin Jiang   +4 more
doaj   +1 more source

Opioids Delay Healing of Spinal Fusion: A Rabbit Posterolateral Lumbar Fusion Model [PDF]

open access: yes, 2018
Background Context Opioid use is prevalent in the management of pre- and postoperative pain in patients undergoing spinal fusion. There is evidence that opioids downregulate osteoblasts in vitro, and a previous study found that morphine delays the ...
Briley, Karen C.   +5 more
core   +1 more source

Brain Characteristics in Patients With Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disorder by 7.0 Tesla MRI

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can radiographically mimic multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). The disease hallmarks cortical lesion, central vein sign (CVS) and paramagnetic rim lesions identified in MS have not yet been comprehensively investigated in ...
Lei Su   +19 more
wiley   +1 more source

Effective Doses of Recombinant Human Bone Morphogenetic Protein-2 in Experimental Spinal Fusion [PDF]

open access: yes, 1996
Study Design Nineteen dogs underwent L4-L5 intertransverse process fusions with either 58 μg, 115 μg, 230 μg, 460 μg, or 920 μg of recombinant human bone morphogenetic protein-2 carried by a polylactic acid polymer.
Dawson, Edgar G.   +7 more
core   +1 more source

Posterior surgical approach procedures for cervical myelopathy [PDF]

open access: yes, 2015
This is the protocol for a review and there is no abstract. The objectives are as follows: The main objective of this review is to assess the effects of laminectomy and fusion versus laminoplasty for multilevel cervical stenosis with myelopathy, on ...
Belloti, João Carlos   +6 more
core   +2 more sources

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova   +5 more
wiley   +1 more source

Instrumented intervertebral or posterolateral fusion in elderly patients Clinical results of a single center

open access: yesBMC Musculoskeletal Disorders, 2011
Background Data on the clinical outcome after spinal fusion in the elderly patient are rare. To our knowledge there has been no clinical outcome assessment for instrumented spinal fusion in elderly patients comparing posterolateral fusion with ...
Wilke Axel, Aigner Rene, Endres Stefan
doaj   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

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