Results 81 to 90 of about 1,534,522 (405)

A Randomized, Controlled Trial of Fusion Surgery for Lumbar Spinal Stenosis.

New England Journal of Medicine, 2016
BACKGROUND The efficacy of fusion surgery in addition to decompression surgery in patients who have lumbar spinal stenosis, with or without degenerative spondylolisthesis, has not been substantiated in controlled trials.
P. Försth, G. Olafsson, T. Carlsson, A. Frost, F. Borgström, P. Fritzell, Patrik Öhagen, K. Michaëlsson, B. Sandén   +8 more
semanticscholar   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Comparing Fusion Rates Between Fresh-Frozen and Freeze-Dried Allografts in Anterior Cervical Discectomy and Fusion

World Neurosurgery: X, 2022
Objective: The objective of this retrospective study is to compare the fusion rates in anterior cervical discectomy and fusion surgery using freeze-dried versus fresh-frozen allografts. Methods: The study comprised 79 patients.
Derron Yu, Paramjyot Singh Panesar, Connor Delman, Benjamin W. Van, Machelle D. Wilson, Hai Van Le, Rolando Roberto, Yashar Javidan, Eric O. Klineberg   +8 more
doaj  

A comprehensive assessment of the risk of bone morphogenetic protein use in spinal fusion surgery and postoperative cancer diagnosis.

Journal of Neurosurgery : Spine, 2015
The risk of postoperative cancer following the use of recombinant human bone morphogenetic protein (BMP)-2 in spinal fusion is one potential complication that has received significant interest.
K. Cahill, P. Mccormick, A. Levi
semanticscholar   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman, Graham F. Barber, S'Dravious A. DeVeaux, Edward A. Botchwey, Daniel Refai, Adam M. Klein, Andrés J. García   +6 more
wiley   +1 more source

Effects of teriparatide and bisphosphonate on spinal fusion procedure: A systematic review and network meta-analysis.

PLoS ONE, 2020
BackgroundGiving patients anti-osteoporotic agents peri-operatively is a well-accepted strategy to increase fusion rate and prevent complications. The purpose of this study was to investigate effectiveness of teriparatide and bisphosphonate on fusion ...
Shih-Hao Cheng, Yi-Jie Kuo, Chiehfeng Chen, Yi-No Kang   +3 more
doaj   +1 more source

Alternative Spinal Fusion Fixation Rod Materials: Polyetheretherketone, Nitinol and Silicon Nitride [PDF]

, 2014
Titanium and its alloys are the most commonly used fixation rod materials in spinal fusion surgery because of their biocompatibility, stability, and endurance.
Dekelbaum, Erik
core   +2 more sources

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Higher incidence of delayed bone fusion for atlantoaxial fusion versus occipitocervical fusion with navigation system

BMC Musculoskeletal Disorders
Background Due to the high stresses placed on the upper cervical spinal region, achieving firm fixation and solid bony fusion is essential for good surgical outcomes.
Masashi Uehara, Shota Ikegami, Hiroki Oba, Terue Hatakenaka, Daisuke Kurogochi, Takuma Fukuzawa, Shinji Sasao, Tetsuhiko Mimura, Jun Takahashi   +8 more
doaj   +1 more source

Minimally Invasive Spinal Fusion Using Percutaneous Pedicle Screw Instrumentation Can Provide a Better Health-Related QOL in Early Stage Than Conventional Methods in the Treatment of Single-Level Degenerative Lumbar Spinal Diseases

Clinical Interventions in Aging, 2023
Masumi Iwabuchi,1 Ryoji Tominaga,1 Jun Komatsu,1,2 Osamu Shirado1 1Department of Orthopaedic and Spinal Surgery, Aizu Medical Center at Fukushima Medical University, Aizuwakamatsu, Fukushima, Japan; 2Department of Medicine for Motor Organs, Juntendo ...
Iwabuchi M, Tominaga R, Komatsu J, Shirado O   +3 more
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