Results 51 to 60 of about 494,812 (295)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Role of Primary Afferents in Arthritis Induced Spinal Microglial Reactivity

Frontiers in Immunology, 2021
Increased afferent input resulting from painful injury augments the activity of central nociceptive circuits via both neuron-neuron and neuron-glia interactions. Microglia, resident immune cells of the central nervous system (CNS), play a crucial role in
Charlie H. T. Kwok, Charlie H. T. Kwok, Yuta Kohro, Yuta Kohro, Yuta Kohro, Michael Mousseau, Michael Mousseau, Melissa S. O’Brien, John R. Matyas, Jason J. McDougall, Tuan Trang, Tuan Trang   +11 more
doaj   +1 more source

Comparative Clinical Effectiveness of Management Strategies for Sciatica: Systematic Review and Network Meta-Analyses [PDF]

, 2013
Background There are numerous treatment approaches for sciatica. Previous systematic reviews have not compared all these strategies together. Purpose To compare the clinical effectiveness of different treatment strategies for sciatica simultaneously.
Rickard, I, Din, N.U., Ud Din, Nafees, Lewis, Ruth, Nafees Ud Din, Phillips, C.J., Phillips, CJ, Williams, N.H., Deborah Fitzsimmons, Nefyn H. Williams, Ruth A. Lewis, Lewis, R, Phillips, Ceri J., Hendry, Maggie, Burton, K., Williams, Nefyn H, Hendry, M., Din, N, Maggie Hendry, Ceri J. Phillips, Hendry, M, Fitzsimmons, Deborah, Nafees, S, Sutton, A., Fitzsimmons, D., Matar, Hosam E., Ceri Phillips, Rickard, Ian, Rickard, I., Ian Rickard, Alex J. Sutton, Matar, H.E., Kim Burton, Wilkinson, C., Sutton, A.J., Hosam E. Matar, Burton, A. Kim, Sadia Nafees, Clare Wilkinson, Lewis, R.A., Nafees, S., Williams, Nefyn, Burton, Anthony, Matar, HE, Fitzsimmons, D, Wilkinson, Clare, Sutton, Alex, Nafees, Sadia   +47 more
core   +1 more source

Electrocapillary Modulated Interfacial Tension Amplifies Liquid Metal Transduction

Advanced Functional Materials, EarlyView.
This study presented an electrocapillary‐enhanced magnetohydrodynamic pumping strategy that harnesses the Lorentz force and interfacial tension modulation of liquid metal droplets to achieve amplified fluidic power. The system enabled low‐voltage, self‐oscillating fluidic transduction with enhanced pressure and flow generation, supporting compact ...
Saba Firouznia, Ciqun Xu, Michael D. Dickey, Jonathan Rossiter   +3 more
wiley   +1 more source

Comparison of transforaminal and interlaminar epidural steroid injections for the treatment of chronic lumbar pain

Revista Brasileira de Anestesiologia
Study design: A cross-sectional study. Objective: We compared the 12 month outcomes of fluoroscopically guided transforaminal epidural steroid injections with interlaminar epidural steroid injections for the treatment of chronic lumbar spinal pain ...
Serbülent Gökhan Beyaz
doaj   +1 more source

Vocational perspectives after spinal cord injury [PDF]

, 2005
Objective: To give insight into the vocational situation several years after a traumatic spinal cord injury (SCI) and describe the personal experiences and unmet needs; to give an overview of health and functional status per type of SCI and their ...
Mulder, G.A., Groothoff, JW, Schönherr, M.C., Schonherr, MC, Groothoff, J.W., Eisma, W.H., Mulder, GA, Eisma, WH   +7 more
core   +2 more sources

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

The Importance of Image Guidance in Common Spine Interventional Procedures for Pain Management: A Comprehensive Narrative Review

Pain and Therapy
Introduction Image-guided spinal injections are commonly performed by pain physicians and supported by literature. A recent survey showed that half of the Canadian providers still perform landmark-guided injections.
Martina Rekatsina, Philip W. H. Peng
doaj   +1 more source

Ultrasound-assisted intrathecal injection of nusinersen in a patient with severe vertebral deformity: a case report

JA Clinical Reports, 2020
Background Spinal muscular atrophy (SMA) is a mostly autosomal recessive genetic disease characterized by progressive muscle weakness from anterior horn degeneration. Nusinersen has recently been approved as a disease-modifying drug for SMA that needs to
Takashi Nagano, Shinichi Sakura, Noritaka Imamachi, Yoji Saito   +3 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source