Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction [PDF]
The brain communicates with the spinal cord through numerous axon tracts that arise from discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination of descending commands.
Blackmore, Murray G. +4 more
core +2 more sources
Managing intrathecal administration of nusinersen in adolescents and adults with 5q-spinal muscular atrophy and previous spinal surgery [PDF]
Background: Spinal muscular atrophy (SMA) is a neurodegenerative disease of lower motor neurons associated with frequent occurrence of spinal deformity.
Rodrigo de Holanda Mendonça +8 more
doaj +2 more sources
Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice [PDF]
Elevated N-methyl-D-aspartate receptor (NMDAR) activity is linked to central sensitization and chronic pain. However, NMDAR antagonists display limited therapeutic potential because of their adverse side effects. Novel approaches targeting the NR2B-PSD95-
Chawla, Aarti +6 more
core +1 more source
Background Spinal epidural lipomatosis is an uncommon source of neurogenic claudication. We present two cases of spinal epidural lipomatosis as it relates to diagnosis, management, and a possible association with common medical intervention.
Keith M. Silcox +4 more
doaj +1 more source
Stem Cell Clinical Trials in Spinal Cord Injury: A Brief Review of Studies in the United States
Background: Although many therapeutic approaches have been attempted to treat spinal cord injury, cellular transplantation offers the greatest promise in reconstituting the architecture of the damaged cord.
Andrew Platt +2 more
doaj +1 more source
Two Cases of Iatrogenic Lumbar Foraminal Disc Herniations
Study Design. A case report. Objective. We report two cases of iatrogenic deterioration of lumbar foraminal disc herniations following lumbar disc injections. Summary of Background Data. Complications associated with discography were reported.
Ryota Taniguchi +4 more
doaj +1 more source
Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat, Rhinolophus rouxi [PDF]
1. Horseradish peroxidase was applied by iontophoretic injections to physiologically identified regions of the laryngeal motor nucleus, the nucleus ambiguus in the CF/FM batRhinolophus rouxi. 2.
Rübsamen, R., Schweizer, Hermann
core +1 more source
Facet joint injections for management of low back pain: a clinically focused review [PDF]
Lumbar facet joints have been implicated in chronic low back pain in up to 45% of patients with low back pain (LBP). Facet joint pain diagnosis and management are always challenging for pain physicians.
Hyung-Sun Won +2 more
doaj +1 more source
Ultrasound Guidance in Paravertebral Injections of Oxygen-Ozone: Treatment of Low Back Pain [PDF]
Background: Paravertebral injection of ozone is an established clinical practice for the treatment of Low Back Pain (LBP). The role of Ultrasound Guidance (USG) in mini invasive procedures has become important in many clinical practice thanks to the ...
Araimo Morselli, FSM +6 more
core +1 more source
Objective: The purpose of this study was to evaluate the accuracy and feasibility of magnetic resonance (MR)-guided periradicular nerve root injection therapy (PRT) using a 0.55 T magnetic resonance imaging (MRI) system with fast dynamic imaging in a ...
Saher Saeed +10 more
doaj +1 more source

