Results 151 to 160 of about 290,143 (362)
Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity
Advanced Science, EarlyView.This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong +16 more
wiley +1 more source
Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries. [PDF]
Proc Natl Acad Sci U S A, 2023 Hamlet C, Fauci L, Morgan JR, Tytell ED.
europepmc +1 more source
Advanced Science, EarlyView.Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng +9 more
wiley +1 more source
Falls on an inpatient rehabilitation spinal injuries unit: the characteristics, circumstances, and consequences. [PDF]
Spinal Cord, 2023 Marshall K +5 more
europepmc +1 more source
CASES OF INJURY TO THE CERVICAL REGION OF THE SPINAL CORD
, 1887 William Thorburn
openalex +1 more source
The school lives of children and young people with a spinal cord injury [PDF]
, 2008 This research study was carried out by the Thomas Coram Research Unit, Institute of Education, University of London, between January and July 2008.The study was funded by The Back-Up Trust, an organisation working with spinally injured adults and ...
Knight, Abigail +3 more
core +1 more source
Advanced Science, EarlyView.Neuromyelitis optica spectrum disorder (NMOSD) has distinct acute‐remitting courses but lacks biomarkers for predicting relapse. Recent studies found cuproptosis‐related genes affect its course, and a model built accordingly can predict relapse to aid intervention.
Peidong Liu +17 more
wiley +1 more source
Air Crash Investigation: Pattern of Spinal Injuries, Management During the COVID-19 Pandemic, and Outcomes. [PDF]
Int J Spine Surg, 2022 Sudarshan P +5 more
europepmc +1 more source
Advanced Science, EarlyView.The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source