The inferior vena caval compression theory of hypotension in obstetric spinal anaesthesia: studies in normal and preeclamptic pregnancy, a literature review and revision of fundamental concepts [PDF]
, 2011 Full metadata records and copyright statements for publications contained in this portfolio thesis are available at the identifiers listedThree clinical investigations together with a combined editorial and review of the cardiovascular physiology of ...
Sharwood-Smith, Geoffrey H.
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Advanced Science, EarlyView.In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang +13 more
wiley +1 more source
Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries. [PDF]
Proc Natl Acad Sci U S A, 2023 Hamlet C, Fauci L, Morgan JR, Tytell ED.
europepmc +1 more source
Advanced Science, EarlyView.Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie +12 more
wiley +1 more source
Integrated spine trauma team protocol: Combined neurosurgical and orthopedic experience for the management of traumatic spinal injuries. [PDF]
J Neurosci Rural Pract, 2023 Giorgi PD +10 more
europepmc +1 more source
Advanced Science, EarlyView.Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai +16 more
wiley +1 more source
Falls on an inpatient rehabilitation spinal injuries unit: the characteristics, circumstances, and consequences. [PDF]
Spinal Cord, 2023 Marshall K +5 more
europepmc +1 more source
CO- TRANSPLANTATION OF BONE MARROW STROMAL CELLS WITH SCHWANN CELLS EVOKES MECHANICAL ALLODYNIA IN THE CONTUSION MODEL OF SPINAL CORD INJURY IN RATS [PDF]
Objective: Several studies have shown that, although transplantation of neural stem cells into the contusion model of spinal cord injury (SCI) promotes locomotor function and improves functional recovery, it induces a painful response, Allodynia ...
جغتایی, محمد تقی +5 more
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Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, EarlyView.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source