Results 181 to 190 of about 202,601 (255)
Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu+11 more
wiley +1 more source
Tele-reHabilitation through Interactive Video Endorsement (THRIVE): An evaluation of using telemedicine to provide post-discharge support for patients with spinal cord injuries [PDF]
Galvin, Kathleen Theresa+2 more
core
Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis
Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley +1 more source
Chinese expert consensus on the treatment of modern combat-related spinal injuries. [PDF]
Zong ZW+15 more
europepmc +1 more source
Abstract Aims Antimicrobial prophylaxis is central in preventing postoperative spine infections, yet knowledge on clinical target spine tissue concentrations remain limited. Current dosing regimens often involve fixed doses based on empirical knowledge, surrogate measures, non‐clinical evidence and methodology of variying quality.
Magnus Andreas Hvistendahl+6 more
wiley +1 more source
Rigour in interpretive qualitative research in education: Ideas to think with
Abstract There has been a proliferation of qualitative approaches to researching education. While this has resulted in the construction of a rich tapestry of knowledge about education, it has also resulted in disparate research ideas, processes and practices, and created tensions relating to what constitutes rigorous qualitative research in education ...
Anthony J. Maher
wiley +1 more source
Traumatic spinal injuries in the Kingdom of Saudi Arabia: a study of associated injuries, management and mortality. [PDF]
Alkhathlan KM+4 more
europepmc +1 more source
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley +1 more source