Results 181 to 190 of about 299,280 (358)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

open access: yesAdvanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang   +9 more
wiley   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

open access: yesAdvanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu   +12 more
wiley   +1 more source

Predictors associated with inappropriate transport of near shore spinal injuries. [PDF]

open access: yesChin J Traumatol, 2021
Lurie T, Traynor T, Bano MS, Tran QK.
europepmc   +1 more source

Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications [PDF]

open access: gold, 2023
Zhen‐Gang Sun   +9 more
openalex   +1 more source

Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug‐Releasing Capability for the Programmable Repair of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
A novel drug‐loaded D/P‐g‐PSB nanogel‐incorporated hydrogel by the electrostatic attraction‐driven self‐assembling process. Sequential drug releasing property (melatonin is released first by physical diffusion, and then ibuprofen is released as the charge shielding effect and hydrogel degradation). This ion‐sensitive hydrogel platform with sequentially
Zhijian Wei   +13 more
wiley   +1 more source

Impact of back protectors on spinal injuries in alpine winter sports: a retrospective cohort study. [PDF]

open access: yesEur J Trauma Emerg Surg
Tinner C   +8 more
europepmc   +1 more source

Adult sports-related traumatic spinal injuries: do different activities predispose to certain injuries? [PDF]

open access: yesJ Neurosurg Spine, 2021
Hauser BM   +11 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy