Results 131 to 140 of about 124,391 (340)

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Association Between Spinal Manipulative Therapy for Low Back Pain With or Without Sciatica and Opioid Use Disorder: A Retrospective Cohort Study

Health Science Reports
Background and Aims Previous research suggests patients receiving spinal manipulative therapy (SMT) for low back pain (LBP) are less likely to be prescribed opioids. However, the clinical implications of this finding are unclear. We tested the hypothesis
Robert J. Trager, Zachary A. Cupler, Jordan A. Gliedt, Ryan A. Fischer, Roshini Srinivasan, Hannah Thorfinnson   +5 more
doaj   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

A Comparison of the Instantaneous Effects of Spinal Manipulation and Mobilization Techniques Applied to L3 Level on Jumping, Agility, and Sprint Speed in Male Volleyball Players

International Journal of Traditional and Complementary Medicine Research
Abstact:Objective: The aim of this study is to investigate the effect of manipulation and mobilization treatments to be applied to the L3 segment on sportive performance in order to prevent athletes' performance anxiety and low performance due to ...
İlker Can Büyükkırlı, Sefa Haktan Hatık, Emine Büşra Aydın   +2 more
doaj   +1 more source

Spinal Manipulation [PDF]

Physical Therapy, 2000
Dave Johnson, Mike Rogers
openaire   +1 more source

Reduction of Current Migraine Headache Pain Following Neck Massage and Spinal Manipulation

, 2012
Younes Jahangiri, Nasibeh Vatankhah, Hamid Reza Baradaran   +2 more
openalex   +2 more sources

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Spinal Manipulation [PDF]

British Journal of General Practice, 2008
openaire   +2 more sources

ASSESSMENT ON THE EFFECTIVENESS OF THORACIC SPINAL MANIPULATION IN PATIENTS WITH MECHANICAL NECK PAIN

, 2019
Nikolay Popov
openalex   +1 more source