Results 91 to 100 of about 14,813 (296)

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

The reliability of chiropractic methods used for the detection of spinal subluxation: An Overview of the literature [PDF]

, 1996
A Literature review was conducted to investigate the methods commonly used to detect chiropractic "subluxation". None were found to show irrefutable reliability and validity.
Walker, B.F.
core   +1 more source

Efficacy of manipulation for non-specific neck pain of recent onset: design of a randomised controlled trial [PDF]

, 2007
Background: Manipulation is a common treatment for non-specific neck pain. Neck manipulation, unlike gentler forms of manual therapy such as mobilisation, is associated with a small risk of serious neurovascular injury and can result in stroke or death ...
Andrew M Leaver, Kathryn M Refshauge, Christopher G Maher, Jane Latimer, Rob D Herbert, Gwendolen Jull, James H McAuley, G Bronfort, AR Gross, ELDCPD Hurwitz, BW Koes, P Sarigiovannis, WS Smith, AGJ Terrett, D Rivett, G Bronfort, JD Cassidy, JR Pikula, DM Rothwell, T Mann, RP DiFabio, SMDPDF Haldeman, N Klougart, PG Shekelle, JN Dunne, E Ernst, JT Robertson, M Magarey, A Michaeli, KM Refshauge, H Merskey, D Trewin, DT Kenny, D Trewin, SV Scrimshaw, HT Vernon, MD Westaway, JE Ware, SJ Pocock, AR Gross, JE Ware, RWJG Ostelo, HCW de Vet, D Kalauokalani, EL Hurwitz   +44 more
core   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Internal carotid artery pseudoaneurysm after neck manipulation in a patient with Eagle syndrome

Clinical Case Reports
Key Clinical Message Contraindications of spinal manipulative therapy (SMT) have been proposed, which mandate rigorous control for its safe practice when manipulating the upper spine.
Ahmed Gamal Sayed, Hesham Aboloyoun, Yasmine Saad Makarem, Ashraf Elnaggar   +3 more
doaj   +1 more source

The effect of spinal manipulative therapy on experimentally induced pain: a systematic literature review

Chiropractic & Manual Therapies, 2012
Background Although there is evidence that spinal manipulative therapy (SMT) can reduce pain, the mechanisms involved are not well established. There is a need to review the scientific literature to establish the evidence-base for the reduction of pain ...
Millan Mario, Leboeuf-Yde Charlotte, Budgell Brian, Amorim Michel-Ange   +3 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study

Chiropractic & Manual Therapies, 2011
Background The objective was to assess the use of the Measure Yourself Medical Outcome Profile (MYMOP2) and W-BQ12 well-being questionnaire for measuring clinical change associated with a course of chiropractic treatment. Methods Chiropractic care of the
Polus Barbara I, Kimpton Amanda J, Walsh Max J   +2 more
doaj   +1 more source

Comparison between high-velocity low-amplitude manipulation and muscle energy technique on pain and trunk neuromuscular postural control in male workers with chronic low back pain: A randomised crossover trial

South African Journal of Physiotherapy, 2020
Background: A therapeutic recommendation for restoring function in individuals with chronic low back pain (CLBP) is manual therapy through manipulative spinal or muscle energy techniques.
Leandro A. Sturion, Alexandre H. Nowotny, Fabrice Barillec, Gilles Barette, Gabriela K. Santos, Fellipe A. Teixeira, Karen P. Fernandes, Rubens da Silva   +7 more
doaj   +1 more source