Results 81 to 90 of about 2,651,862 (278)

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

Comparison of General Exercises, Motor Control Exercises and Spinal Manipulation in Chronic Low Back Pain Patients

Pakistan Armed Forces Medical Journal
Objective: To compare the effects of motor control exercises, general exercises and spinal manipulative therapy on pain, functional status and disability in chronic low back pain patients. Study Design: Randomized Clinical Trial (IRCT:20200511047391N1)
Ammara Khalid, Naveed Anwar, Sana Tauqeer, Kehkhshan Khalid, Ayesha Zakir, Sidra Munir   +5 more
doaj   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Internal carotid artery pseudoaneurysm after neck manipulation in a patient with Eagle syndrome

Clinical Case Reports
Key Clinical Message Contraindications of spinal manipulative therapy (SMT) have been proposed, which mandate rigorous control for its safe practice when manipulating the upper spine.
Ahmed Gamal Sayed, Hesham Aboloyoun, Yasmine Saad Makarem, Ashraf Elnaggar   +3 more
doaj   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

The effect of spinal manipulative therapy on experimentally induced pain: a systematic literature review

Chiropractic & Manual Therapies, 2012
Background Although there is evidence that spinal manipulative therapy (SMT) can reduce pain, the mechanisms involved are not well established. There is a need to review the scientific literature to establish the evidence-base for the reduction of pain ...
Millan Mario, Leboeuf-Yde Charlotte, Budgell Brian, Amorim Michel-Ange   +3 more
doaj   +1 more source

Manipulative Therapy for Lower Extremity Conditions: Expansion of Literature Review

, 2009
Objective: The purpose of this study was to conduct a systematic review on manipulative therapy for lower extremity conditions and expand on a previously published literature review.
Pollard, Henry, Hicks, Marian, Korporaal, Charmaine, Hoskins, Wayne, Brantingham, James W, Globe, Gary   +5 more
core   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study

Chiropractic & Manual Therapies, 2011
Background The objective was to assess the use of the Measure Yourself Medical Outcome Profile (MYMOP2) and W-BQ12 well-being questionnaire for measuring clinical change associated with a course of chiropractic treatment. Methods Chiropractic care of the
Polus Barbara I, Kimpton Amanda J, Walsh Max J   +2 more
doaj   +1 more source

CLUSTER RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE EFFECTIVENESS OF A MULTIFACETED ACTIVE STRATEGY TO IMPLEMENT LOW BACK PAIN PRACTICE GUIDELINES; EFFECT ON COMPETENCE, PROCESS OF CARE AND PATIENT OUTCOMES IN PHYSICAL THERAPY [PDF]

, 2013
The study was a cluster randomized controlled trial designed to evaluate the effectiveness of an active strategy to implement practice guidelines for low back pain in physical therapy.
Shenoy, Sonali
core