Results 201 to 210 of about 120,291 (395)
Evaluating Perceived Fatigue within an Adult Spinal Muscular Atrophy Population [PDF]
, 2023 Lisa Belter, Ilse Peterson, Jill Jarecki
openalex +1 more source
Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks
Chemistry – A European Journal, EarlyView.A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan +8 more
wiley +1 more source
SMN Deficiency Destabilizes ABCA1 Expression in Human Fibroblasts: Novel Insights in Pathophysiology of Spinal Muscular Atrophy [PDF]
, 2023 Francesca Gabanella +11 more
openalex +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
Cytoskeleton, EarlyView.ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Air stacking: effects on pulmonary function in patients with spinal muscular atrophy and in patients with congenital muscular dystrophy, [PDF]
, 2014 Tanyse Bahia Carvalho Marques +5 more
openalex +1 more source
Pigment‐Macromolecule Complexes Isolation from Sea Urchin Biomineral Waste for Coloring Materials
Chemistry–Methods, EarlyView.A methodology has been developed to extract the colored organic fraction occluded within seashell biomineral waste. Applied to sea urchin skeletons, free polyhydroxylated naphthoquinone (PHNQ) pigments and PHNQ‐macromolecule complexes are isolated. These complexes show superior pH stability in purple hues compared to free PHNQ, which shifts from red to
Claudio Ferreira +12 more
wiley +1 more source
Population-based Carrier Screening for Spinal Muscular Atrophy in Saudi Arabia [PDF]
, 2021 Mohammed Al Jumah +7 more
openalex +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee +5 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.In this review, the application of micro‐CT and medical‐CT scanning in the oil and gas industry has been thoroughly discussed. Recent improvements in DRP and modern imaging techniques in the oil and gas industry have been modeled using both experimental and simulation work.
Achinta Bera +2 more
wiley +1 more source