Results 71 to 80 of about 77,106 (331)
Advanced Materials, EarlyView.In this study, a vaginal specific ECM hydrogel (vECM) is developed, optimized for intravaginal topical administration, and evaluated for mitigatation of vaginal atrophy associated with menopause. When applied in a rat model of menopause, vECM improves vaginal epithelial thickness and stem cell phenotype, and despite topical application, vECM also ...
Emma I. Zelus +6 more
wiley +1 more source
Archives of Health Science and ResearchObjective: This study aimed to compare the mechanical properties of upper and lower extremities between children with spinal muscular atrophy types 1 and 2 and healthy peers.
Seval KUTLUTÜRK-YIKILMAZ +3 more
doaj +1 more source
Spinal Muscular Atrophy and Arthrogryposis
Pediatric Neurology Briefs, 1997 Four infants with neurogenic arthrogryposis who died of respiratory failure before 1 month of age had DNA testing of autopsy specimens for SMNT gene deletion in a study at the Children’s Hospital of Philadelphia, PA, and the Children’s Hospital at ...
J Gordon Millichap
doaj +1 more source
The First Orally Deliverable Small Molecule for the Treatment of Spinal Muscular Atrophy
Neuroscience Insights, 2020 Spinal muscular atrophy (SMA) is 1 of the leading causes of infant mortality. SMA is mostly caused by low levels of Survival Motor Neuron (SMN) protein due to deletion of or mutation in the SMN1 gene.
R. Singh, E. Ottesen, N. Singh
semanticscholar +1 more source
Advanced Materials, EarlyView.It provides an overview of the synthesis of organic/inorganic nanocomposites, spanning from conventional methods to advanced 3D printing techniques. It summarizes key challenges in 3D‐printed nanocomposites and highlights emerging innovations, including 5D printing, AI‐assisted material design, nanoscale additive manufacturing, and sustainable closed ...
Liwen Zhang +8 more
wiley +1 more source
3D Printing for Neural Repair: Bridging the Gap in Regenerative Medicine
Advanced Materials, EarlyView.This perspective article discusses how 3D bioprinting is advancing the development of neural tissue models and implants. It highlights recent progress in fabricating complex, multicellular neural constructs, examines current technical barriers, and outlines future applications in disease modeling, neurotoxicity testing, and regenerative therapies ...
Mitchell St Clair‐Glover +2 more
wiley +1 more source
Spinal muscular atrophy (Werdnig‑Hoffmann atrophy disease) [PDF]
Archives of the Balkan Medical Union, 2018 Introduction. Spinal muscular atrophy type 1 is an autosomal recessive neuromuscular disorder characterized by degeneration of the anterior horn cells in the spinal cord, leading to symmetric muscle weakness and atrophy.
Mariana A. RYZNYCHUK +4 more
doaj
Advanced Materials Technologies, EarlyView.A flexible, lightweight ankle brace made from 3D‐printed liquid crystal polymer metamaterials offers targeted support without restricting movement. Programmable stiffness provides protection during risky motions. Biomechanical tests suggest performance comparable to commercial braces with reduced bulk, highlighting potential for broader orthotic ...
Cassi J. Henderson +5 more
wiley +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Rehabilitation in spinal muscular atrophy
The Journal of the International Society of Physical and Rehabilitation Medicine, 2019 Spinal muscular atrophy (SMA) is an autosomal recessive disorder with symptoms of progressive skeletal muscular atrophy which requires multidisciplinary medical care.
Agus Iwan Foead +3 more
doaj +1 more source