A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang +13 more
wiley +1 more source
Anterior Corpectomy and Vertebroplasty With Carbon-Polyetheretherketone (PEEK) Cage for Invasive Spinal Meningioma. [PDF]
Hall B, Anderson P, Christiano LD.
europepmc +1 more source
Neuronal differentiation and tissue engineering strategies for central neurous system injury repair
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia +9 more
wiley +1 more source
Evaluation of magnetic resonance imaging and deep learning-based synthetic computed tomography for calcified intradural tumors - importance of domain-specific training and validation of synthetic imaging methods for clinical application. [PDF]
Fischer G +7 more
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Evolutionary origins of spinal cord tumors: A cross-species systematic review. [PDF]
Urreola G +7 more
europepmc +1 more source
Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
Giant Cell Tumor in the Thoracolumbar Junction: A Case Report. [PDF]
Villalba-Piña VM +3 more
europepmc +1 more source

