Results 241 to 250 of about 903,662 (366)

Thoracic spinal epidural angiolipoma presenting with progressive paraparesis in an elderly patient. [PDF]

Surg Neurol Int
Gok H, Yangi K, Alomari O, Hacisalihoglu UP.   +3 more
europepmc   +1 more source

Late‐Onset Spondylarthritis Presenting as Glucocorticoid‐Resistant Polymyalgia Rheumatica: A hitherto underappreciated entity where TNF or IL‐17 Blockade may have a Therapeutic Role

Arthritis &Rheumatology, Accepted Article.
Background Polymyalgia rheumatica (PMR) is an age‐related inflammatory disease with shoulder‐hip girdle involvement. Magnetic resonance imaging (MRI) reveals extracapsular/entheseal soft tissue involvements in both PMR and spondyloarthritis (SpA) with sacroiliac joint and peri‐entheseal spinal bone marrow oedema (BMO) being characteristic of SpA ...
Kerem Abacar, Gabriele De Marco, Jake Weddell, Katya Meridor, Tom Macleod, Andrew Scarsbrook, Kulveer Mankia, Edward Vital, Andrew Barr, Colin Pease, Helena Marzo‐Ortega, Sarah L. Mackie, Dennis McGonagle   +12 more
wiley   +1 more source

Electrochemotherapy of spinal metastasis using transpedicular approach: a preclinical safety animal study. [PDF]

Eur Radiol Exp
Deschamps F, Gautreau E, Tselikas L, Bonnet B, Beunon P, Feddal A, de Baere T, Gaudin A, Mir LM.   +8 more
europepmc   +1 more source

A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome

Autism Research, EarlyView.
ABSTRACT Although there are as many as 40 preclinical models of the neurodevelopmental disorder Phelan McDermid syndrome (PMS, or 22q13.3 deletion syndrome), detailed phenotypic analyses to compare the effects of different pathogenic variants and inform treatment design are lacking.
Vic Lin, Samantha M. Matta, Julia E. Dallman, Suzanne Hosie, Manon Moreau, Ashley E. Franks, Thomas Bourgeron, Elisa L. Hill‐Yardin   +7 more
wiley   +1 more source

Racial and socioeconomic disparities in long term survival after surgery and radiation for spinal cord hemangioblastoma. [PDF]

Sci Rep
Ghaith AK, Yang X, Weinberg J, Bhandarkar S, Khalilullah T, Al-Mistarehi AH, Zaitoun K, Bhimreddy M, Menta AK, Fuleihan A, Chebaro K, Khalifeh J, Grossbach A, Theodore N, Lubelski D.   +14 more
europepmc   +1 more source

Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social interactions, repetitive behaviors, and hyper‐ or hyposensitivity to sensory stimuli. The cellular mechanisms underlying the emergence of abnormal sensory sensitivity in ASD are not fully understood.
Alejandra Fernandez, Nick Sarn, Charis Eng, Kevin M. Wright   +3 more
wiley   +1 more source

The efficacy of 5.5-mm diameter rods combined with cervical pedicle screws for the treatment of challenging spinal disease in cervicothoracic junction: Is it a game-changer? [PDF]

Medicine (Baltimore)
Oh Y, Lee S, Lee SH, Park D, Kim C, Jang SW, Park JH.   +6 more
europepmc   +1 more source

Dose individualisation of antibiotics in critically ill patients with inflammation: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Due to extensive pathophysiological changes in critically ill patients, standard dosing of antibiotics may lead to inadequate drug exposure. This is concerning, as insufficient plasma drug concentrations may lead to treatment failure, whereas excessive drug exposure may increase the risk of toxic adverse events.
Sarah Dräger, Iris K. Minichmayr, Narges Alipanah‐Lechner, Erin F. Barreto, Lieuwe D. J. Bos, Lucas M. Fleuren, Nicole G. M. Hunfeld, Sumith K. Mathew, Sophie L. Stocker, João Paulo Telles, Antoni Torres, Birgit C. P. Koch, Henrik Endeman   +12 more
wiley   +1 more source

Ultrasonography diagnosis of dumbbell-shaped C5 cervical schwannoma: a case report and literature review. [PDF]

Front Oncol
Yu K, Chen J, Pan M, Xu K, Huang P, Peng Y.   +5 more
europepmc   +1 more source

How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration

BioEssays, EarlyView.
Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa, Chikako Nakajima, Masato Sawada, Kazunobu Sawamoto   +3 more
wiley   +1 more source