Results 111 to 120 of about 74,410 (312)

Conjoined Lumbosacral (L7-S1) Nerve Roots in a Dog

Anatomia
Vertebral and spinal cord anomalies are well known in veterinary medicine. However, nerve root anomalies are seldomly reported. In human patients, nerve root anomalies can cause back pain and radicular pain.
Esther Lichtenauer, Koen Santifort, Dorien Willems, Vicente Aige-Gil, Niklas Bergknut   +4 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Less False Negative in Neuromonitoring Lumbar Screws

Global Spine Journal, 2016
Introduction IOM is a standard care in cases of scoliosis.. there is more controversial their use in mubar pathology.. there are 5% lessions of nerve roots.
Pedro Cortes Garcia, Pedro Perez Lorensu, Bernabe Deniz Rodriguez   +2 more
doaj   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review

Journal of Blood Medicine, 2021
Justin J Kuhlman,1 Muhamad Alhaj Moustafa,2 Vivek Gupta,3 Liuyan Jiang,4 Han W Tun2 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic Florida, Jacksonville, FL, USA ...
Kuhlman JJ, Alhaj Moustafa M, Gupta V, Jiang L, Tun HW   +4 more
doaj  

The Effects of Serotonin on Functionally Diverse Isolated Lamprey Spinal Cord Neurons [PDF]

, 2002
The experiments reported here showed that application of serotonin (5-hydroxytryptamine, 5-HT) (100 µ M) did not induce any significant current through the membranes of any of the spinal neurons studied (n = 62).
Batueva, I. V., Buchanan, James T., Suderevskaya, E. I., Tsvetkov, E. A., Veselkin, N. P.   +4 more
core   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Spinal schwannoma presenting with intraspinal hematoma: a case report and review of the literature

Journal of Medical Case Reports
Background Spinal schwannomas presenting with an intraspinal hematoma or subarachnoid hemorrhage are extremely rare, and patients often have severe spinal cord compression symptoms. However, the mechanism underlying the bleeding remains unclear.
Zhe Shen, Haoyang Chen, Haosheng Wang, Yaoqi Wang, Tao Li   +4 more
doaj   +1 more source

18F-FDG PET/CT in Neurolymphomatosis: Report of 3 Cases [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2014
Neurolymphomatosis is a rare manifestation of non-Hodgkin lymphoma characterized by infiltration of peripheral nerves, nerve roots, plexus and cranial nerves by malignant lymphocytes. This report presents positron emission tomography/computed tomography (
Nguyen Xuan Canh, Ngo Van Tan, Tran Thanh Tung, Nguyen Truong Son, Simone Maurea   +4 more
doaj