Status and future of recombinant adeno‐associated virus vector manufacturing
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Sciatic and Posterior Femoral Cutaneous Nerve Anomalies and Their Clinical Implications for Sciatica and Piriformis Syndrome: A Cadaveric Case Report. [PDF]
Reaux C +5 more
europepmc +1 more source
Anatomical Study and Classification of Foramina of the Squamous Part of the Temporal Bone
ABSTRACT The postglenoid foramen (PGF) is a rarely reported anatomical variant of the temporal bone, with limited data on its morphology, prevalence, and clinical relevance, particularly in non‐European populations. This study aimed to investigate the anatomy and frequency of foramina located on the squamous part of the temporal bone, including the PGF,
Tawanrat Paensukyen +7 more
wiley +1 more source
Little Known Facts, Controversies and Misconceptions About Cranial Motor Nuclei (and a New Classification for All Motoneurons, Cranial, and Spinal). [PDF]
Sivori M, Dempsey B, Brunet JF.
europepmc +1 more source
ABSTRACT Myofascial pain syndrome (MFPS) causes chronic shoulder pain. Supraspinatus and infraspinatus, rotator cuff muscles innervated by the suprascapular nerve, are commonly affected. Intramuscular botulinum neurotoxin (BoNT) injections near motor points (i.e., visible nerve branch entry sites used as a proxy for motor endplates) are an effective ...
Dave Osinachukwu Duru +5 more
wiley +1 more source
Exploring Variations in Median Nerve Formation: Embryological Basis and a Pathway to Improved Clinical Outcomes. [PDF]
Venkateswar S, Ramachandran K.
europepmc +1 more source
The Cutaneous Branch of the Obturator Nerve: Common Finding or a Rarity Worthy of Note
ABSTRACT According to textbook descriptions, branches of the femoral and obturator nerves provide the sensory innervation to the medial side of the thigh. However, as the exact prevalence of the obturator nerve's cutaneous branch is unknown, an anatomic study was conducted to reveal its role in providing cutaneous innervation to the medial thigh ...
Christoph Fuchssteiner +3 more
wiley +1 more source
Magnetic Resonance Imaging of Nerve Roots in the Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) - A Systematic Review and Meta-Analysis. [PDF]
Gausmann KM +5 more
europepmc +1 more source
Grooved Surface of the Obturator Internus Muscle With Two Distinct Adjacent Parts
ABSTRACT The specific anatomical features of the obturator internus, particularly those of its medial surface, remain insufficiently characterized. This study investigated the morphology of the obturator internus muscle by focusing on the shape of its medial surface and potential age‐related changes.
Satoru Muro +4 more
wiley +1 more source

