Results 101 to 110 of about 582,656 (221)

Inhibition of METTL14 Alleviates OGD/R‐Induced Neuronal Differentiation Injury in Neural Stem Cells Through Suppressing the Tp53inp2/Ptgs2 Axis: Potential Benefits for the Mouse MCAO Model

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The graphical abstract highlights that ischemic stroke leads to increased METTL14 expression, which enhances Tp53inp2 mRNA stability through m6A modification. Elevated Tp53inp2 then promotes damaging mitophagy and ROS production by upregulating Ptgs2, ultimately impairing the neuronal differentiation of neural stem cells.
Dan Hou   +4 more
wiley   +1 more source

Rifapentine- and moxifloxacin-containing short-course regimens for mild spinal tuberculosis: study protocol for a multicenter, randomized, non-inferiority phase II clinical trial

open access: yesFrontiers in Pharmacology
BackgroundSpinal tuberculosis is the most common form of osteoarticular infection, with recommended anti-tuberculosis treatment durations typically being long (9–18 months), even for mild cases, increasing the risks of drug resistance, toxicity, and poor
Yue-E Wu   +19 more
doaj   +1 more source

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 7, Page 1729-1735, September 2026.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

1970 Tuberculosis Statistics : States And Cities [PDF]

open access: yes
In previous years, annual editions of \u201cReported Tuberculosis Data" presented detail and summary tables by geographic areas, and a review of tuberculosis statistics for the United States.

core  

Miliary Tuberculosis Diagnosed After Repeated Sputum Smear Examinations Despite Negative Results at a Referral Tuberculosis Center: The Importance of Maintaining Clinical Suspicion

open access: yesJournal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT An 88‐year‐old woman with back pain was found to have destructive changes at T9/T10 and diffuse micronodular pulmonary opacities suggestive of miliary tuberculosis. At two referring hospitals, six sputum smears and two interferon‐gamma release assays were negative.
Kento Kabeya   +2 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang   +13 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter   +20 more
wiley   +1 more source

Tuberculosis and pregnancy Spanish

open access: yes
"Para una mujer embarazada y su criatura, la tuberculosis no tratada constituye un riesgo mayor que el propio tratamiento. Las mujeres embarazadas deben comenzar a tratarse cuando su probabilidad de tener tuberculosis sea de moderada a elevada.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.) Division of Tuberculosis Elimination.
core  

Intrathecal Chemotherapy Through Ommaya Reservoir in Leptomeningeal Metastasis From Cervical Cancer: A Rare Case Report and Literature Review

open access: yesJournal of Obstetrics and Gynaecology Research, Volume 52, Issue 9, September 2026.
ABSTRACT Leptomeningeal metastasis (LM) is a rare complication of cervical cancer associated with a poor prognosis. We report a 61‐year‐old woman with stage IVB cervical squamous cell carcinoma who developed acute headache and diplopia during systemic chemotherapy.
Chery Ahn   +7 more
wiley   +1 more source

Clinical Efficacy and Learning Curve of Far‐Lateral Approach (FLA) in Uni‐Portal Non‐Coaxial Spinal Endoscopic Surgery (UNSES) in the Treatment of Lumbar Degenerative Diseases: A Prospective Study

open access: yesOrthopaedic Surgery, Volume 18, Issue 9, Page 1972-1980, September 2026.
UNSES via FLA is a safe and effective minimally invasive technique for treating complex lumbar degenerative diseases. It has a certain learning curve, and the inflection point is about the 16th case. After mastering the key techniques such as anatomical positioning, endoscopic manipulation and hemostasis, the surgeon can gradually reach the proficiency
Mengchen Yin   +12 more
wiley   +1 more source

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