Results 131 to 140 of about 93,060 (311)

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

open access: yesAdvanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan   +21 more
wiley   +1 more source

Statistical model of the tool/workpiece mechanical interactions in FSW [PDF]

open access: yes, 2012
The robotization of the FSW process is facing two challenges which are to support the amplitude of the tool / workpiece mechanical interaction generated by welding and to apply the process parameters and in particular the axial force.
ABBA, Gabriel   +4 more
core   +3 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

BEARING WEAR ANALYSIS IN MULTI-BEARING SPINDLE SYSTEM

open access: yesJixie qiangdu, 2021
In order to clarify the effects of different working condition parameters and quantify their influence degree on bearing wear in the spindle system, the bearing wear in the spindle system supported by multi-bearing was carried out.
ZHANG Yu   +3 more
doaj  

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang   +8 more
wiley   +1 more source

Investigation on influence of cutting parameters on spindle vibration of CNC wood milling machine

open access: yesMATEC Web of Conferences, 2018
In machining operation, the cutting parameters greatly influences on the spindle vibration of a CNC wood milling machine. The paper presents the effect of the cutting parameters such as feed rate, cutting speed, and cutting depth on the vibration ...
Van Thuy Tran, Nguyen Huu Loc
doaj   +1 more source

HIDF: Integrating Tree‐Structured scRNA‐seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou   +5 more
wiley   +1 more source

COMPUTER SIMULATION OF VIBRATION SURVEILLANCE OF DISCRETELY IDEALISED MECHANICAL SYSTEMS. PART II: TOOL-WORKPIECE VIBRATION IN A NON-STATIONARY MODEL OF THE CUTTING PROCESS

open access: yesTASK Quarterly, 2004
The problems of tool-workpiece vibration surveillance during machining have been researched. The object of investigation has been analysed, and cutting dynamics and calculation model creation described.
KRZYSZTOF J. KALIŃSKI
doaj  

Intelligent Stain‐Free Histology on Structural Colorimetric Nanocavities

open access: yesAdvanced Science, EarlyView.
Chen and Gan et al. introduce a label‐free imaging platform using inexpensive Nanocavity‐on‐Silicon (NOS) slides. These slides transform subtle tissue variations into vivid structural colors, enabling high‐contrast histological imaging under a regular optical microscope. This stain‐free approach reveals morphological details comparable to traditional H&
Qizhe Chen   +18 more
wiley   +1 more source

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