Results 91 to 100 of about 651,239 (267)

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source

Development of a Physiologic In-Vitro Testing Methodology for Assessment of Cervical Spine Kinematics [PDF]

, 2013
In-vitro biomechanical testing has been critical in the design and evaluation of spinal surgical instrumentation, however determination of realistic physiologic loading levels has proven difficult outside of the in-vivo setting.
Bell, Kevin
core  

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Multiple Regression Analysis of Factors Affecting the Mental Component Score Constituents of SF-36 in Adult Spinal Deformity

Global Spine Journal, 2016
Introduction As surgical decision-making and preoperative planning for adult spinal deformity (ASD) need strongly be interrelated to health related quality of life (HRQOL), there are multiple studies focusing on factors with an impact on it. Based on the
Selim Ayhan, Selcem Yuksel, Asli Niyazi, Vugar Nabiyev, Ümit Özgür Güler, Tiro Mmopelwa, Montse Domingo Sabat, Ferran Pellise, Ahmet Alanay, Francisco Javier Sanchez Perez-Grueso, Frank Kleinstuck, Ibrahim Obeid, Emre Acaroglu,   +13 more
doaj   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Swespine: the Swedish spine register : The 2012 report. [PDF]

, 2013
Swespine, the Swedish National Spine Register, has existed for 20 years and is in general use within the country since over 10 years regarding degenerative lumbar spine disorders.
Sandén, Bengt,, Peter Fritzell, Bengt Sandén, Fritzell, Peter, Björn Strömqvist, Sandén, Bengt, Jönsson, Bo, null null, Bo Jönsson, Hägg, Olle, Olle Hägg, Strömqvist, Björn,, Lund University., Strömqvist, Björn, Jönsson, Bo,   +14 more
core   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Cervicothoracic-upper thoracic three-column osteotomy for treatment of proximal junctional failures following adult spinal surgery

Brain and Spine, 2021
Recep Dincer, Sina Coskun, Ahmet Ates, Mustafa Eltayep, Ugur Tasci, Seray Gur, Ayhan Mutlu, Tunay Sanli, Sinan Kahraman, Selhan Karadereler, Meric Enercan, Azmi Hamzaoglu   +11 more
doaj   +1 more source

Advanced Technique of Unilateral Biportal Endoscopy on Revision Surgery for Recurred Herniated Interverbral Disc: A Technical Note

Case Reports in Orthopedics
Conclusion: Lumbar UBE offers a promising option for safe and effective reoperation in spinal surgery. Our technique, emphasizing bone-centered manipulation and specific strategies for scar tissue management, provides excellent visibility and enables ...
Hun-Chul Kim, Jin Young Lee, Hyeon Guk Cho, Jeong Woo Park, Sang-Ho Han, Young-Il Ko   +5 more
doaj   +1 more source

Exosomes from Bone Marrow Mesenchymal Stem Cells Inhibit Neuronal Apoptosis and Promote Motor Function Recovery via the Wnt/β-catenin Signaling Pathway

Cell Transplantation, 2019
Severe spinal cord injury (SCI) is caused by external mechanical injury, resulting in unrecoverable neurological injury. Recent studies have shown that exosomes derived from bone marrow mesenchymal stem cells (BMSCs-Exos) might be valuable paracrine ...
Ci Li, Guangjun Jiao, Wenliang Wu, Hongliang Wang, Shanwu Ren, Lu Zhang, Hongming Zhou, Haichun Liu, Yunzhen Chen   +8 more
doaj   +1 more source