Results 221 to 230 of about 107,650 (257)

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Editorial: Rising stars in neurosurgery 2025. [PDF]

Front Surg
Kumar KK, Rahmani R, Esene I, Wu H, Stienen MN.   +4 more
europepmc   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

Advances in Metastatic Disease Spinal Oncology: Novel Technology Without Forgetting the Fundamentals of Surgical Treatment. [PDF]

Neurospine
Jain H, Ahluwalia R, Laufer I, Zuckerman SL.   +3 more
europepmc   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source

Taxonomic revision of two dominant <i>Munidopsis</i> species (Decapoda, Anomura, Munidopsidae) from the cold seeps in the northern South China Sea: new records and complementary descriptions. [PDF]

Zookeys
Dong D, Seid CA, Li X, Rouse GW.
europepmc   +1 more source

Mouse and human striatal projection neurons compared - somatodendritic arbor, spines and in silico analyses. [PDF]

PLoS Comput Biol
Kozlov A, Blazquez-Llorca L, Benavides-Piccione R, Kastanauskaite A, Rojo AI, Muñoz A, Cuadrado A, DeFelipe J, Grillner S.   +8 more
europepmc   +1 more source

TAPT1 interacts with SUCO to maintain the homeostasis of newly synthesized proteins and brain development in mice. [PDF]

Proc Natl Acad Sci U S A
Gao J, Yang F, Jiang Y, Zheng Y, Cai L, Huang X, Yuan L, Wang Y, Wang Y, Xu Z.   +9 more
europepmc   +1 more source

Trans-Generational Morphological Trait Plasticity in Parthenogenetic Offspring of Two <i>Brachionus dorcas</i> Morphotypes Induced by <i>Asplanchna</i> Kairomones. [PDF]

Ecol Evol
Ge Y, Zhu J, Ren Y, Wu X, Zhou B, Wu Y, Ge Y.   +6 more
europepmc   +1 more source

Genetic Markers and Mutations in Primary Spinal Cord Tumors and Their Impact on Clinical Management. [PDF]

Brain Sci
Motiei-Langroudi R.
europepmc   +1 more source