Results 61 to 70 of about 42,556 (266)

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis [PDF]

open access: yes, 2015
International audienceBy regulating actin cytoskeleton dynamics, Rho GTPases and their activators RhoGEFs are implicated in various aspects of neuronal differentiation, including dendritogenesis and synaptogenesis. Purkinje cells (PCs) of the cerebellum,
Raynaud, Fabrice   +21 more
core   +1 more source

Correlation between Iliac Tilt and traditional sagittal parameters in adolescents

open access: yesJournal of Orthopaedic Surgery and Research
Objective This study aims to systematically validate the reliability and applicability of Iliac Tilt (IT) as a parameter for sagittal balance assessment, explore its relationship with traditional parameters such as Pelvic Tilt (PT) and Pubic-Sacral Angle
ZengHui Zhao   +7 more
doaj   +1 more source

Biologic Targets for Mitigating Age-Associated Intervertebral Disc Degeneration

open access: yesGlobal Spine Journal, 2016
Growing old is the greatest risk factor for the development of intervertebral disc degeneration (IDD), an underlying condition of many debilitating spine-related disorders including chronic back pain.
Nam Vo
doaj   +1 more source

Fast Charge–Discharge of LiNi0.9Co0.05Mn0.05 Enabled by a Bikitaite‐Infused Separator for Li Metal Batteries

open access: yesAdvanced Functional Materials, EarlyView.
A bikitaite‐infused cellulose separator is introduced for Li metal batteries, leveraging bikitaite zeolite's ion‐conductive properties to regulate Li+‐ion flux and suppress dendrite growth. The membrane design ensures uniform Li plating, enhanced electrolyte wettability, and robust thermal/mechanical stability, delivering stable performance and low ...
Isheunesu Phiri   +2 more
wiley   +1 more source

The biology of the ovine functional spinal unit: facet cartilage and intervertebral disc [PDF]

open access: yes, 2013
Back pain will affect up to 84 % of people at some point in their lives. It is a major public health problem in Western society leading to disability and economic loss through work absence, physician visits and hospitalisation.
Gough, Caroline Shanni
core  

Identification of an Allosteric Signaling Network within Tec Family Kinases

open access: yes, 2010
The Tec family kinases are tyrosine kinases that function primarily in hematopoietic cells. The catalytic activity of the Tec kinases is positively influenced by the regulatory domains outside of the kinase domain.
Raji E. Joseph   +5 more
core   +1 more source

The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease [PDF]

open access: yes, 2012
A significant amount of evidence suggests that the p38-mitogen-activated protein kinase (MAPK) signalling cascade plays a crucial role in synaptic plasticity and in neurodegenerative diseases.
Eales, Katherine L.   +1 more
core   +1 more source

3D Printing Innovations in Polymeric Porous and Patterned Architecture

open access: yesAdvanced Functional Materials, EarlyView.
Polymeric foams occupy a unique structural space between dense solids and open networks, where engineered void fraction governs mechanical compliance, thermal resistance, and mass transport. Additive manufacturing now enables precise spatial control over cellular architecture, unlocking designer foam structures across applications spanning crash ...
Dhanush Patil   +13 more
wiley   +1 more source

Palmitoylation of cdc42 Promotes Spine Stabilization and Rescues Spine Density Deficit in a Mouse Model of 22q11.2 Deletion Syndrome [PDF]

open access: yes, 2021
22q11.2 deletion syndrome (22q11DS) is associated with learning and cognitive dysfunctions and a high risk of developing schizophrenia. It has become increasingly clear that dendritic spine plasticity is tightly linked to cognition.
Muller, D.   +6 more
core  

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy