Results 181 to 190 of about 1,782,642 (314)

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

What are the Real Achievements in Spine Surgery? [PDF]

Global Spine J
Chapman JR, Wang JC, Wiechert K.
europepmc   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Clinical Risk Stratification and Neutrophil-Mediated Neuroinflammation in Myeloid Hypertension-Like Syndrome: An Integrated Clinical and Single-Cell Transcriptomic Study

International Journal of Clinical Practice
Qisong Shang, Haopeng Luan, Pengyuan Han, Xiaonan Wang, Junru Zheng, Xing Wang, Xinghua Song   +6 more
doaj   +1 more source

Clinical and Radiological Outcomes of Single-Level Full Endoscopic Posterior Cervical Foraminotomy and Herniectomy: A 12 months Follow-up

Orthopedic Research and Reviews
Hung The Dinh,1,2,* Son Ngoc Dinh,1,2,* Long Hoang Nguyen,2 Hung Manh Do,2 Thach Van Nguyen,2 Cuong Van Vu2 1Faculty of Surgery, Ha Noi Medical University, Hanoi, Vietnam; 2Department of Spine Surgery, Viet Duc University Hospital, Hanoi,
The Dinh H, Ngoc Dinh S, Hoang Nguyen L, Manh Do H, Van Nguyen T, Van Vu C   +5 more
doaj  

Predictive Analysis of Social Determinants of Health in Posterior Cervical Spine Surgery. [PDF]

J Clin Med
Mittal M, Jain R, Tennyson JM, Kumar D, Bajaj PM, Reyes SG, Hsu WK, Patel AA, Divi SN.   +8 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

CYP2D6 Metabolizer Phenotype and New Persistent Opioid Use After Spine Surgery. [PDF]

Global Spine J
Salman SG, Phadke RA, Anand KK, Guarnieri JW, Waisberg E, Rizkalla J, Lee NJ.   +6 more
europepmc   +1 more source

Geometry‐Encoded Soft Strain Sensing via Liquid‐Metal Transmission Lines

Advanced Science, EarlyView.
This study presents a liquid‐metal transmission‐line strain sensor that achieves intrinsic decoupling by encoding axial elongation into propagation delay. The time‐domain readout remains stable under complex off‐axis. This enables reliable, repeatable, real‐time elongation measurement in dynamic, multiaxial loading environments for wearable electronics,
Zhang Liu, Fengdeng Jin, Wenxuan Shi, Meng She, Ziqi Meng, Miao Fang, Yixin Zhang, Qianwen Dong, Wandi Yang, Lei Shi, Xujia Zhao, Feng Zhou, Bin Yao   +12 more
wiley   +1 more source

National Medicare trends in navigation-assisted spine surgery: A temporal and geographic analysis. [PDF]

J Craniovertebr Junction Spine
Sanghera BS, Mohiuddin MK, Shah KH, Peterson-Hester M, Cummings A, Errante EL, Levy AS, Khalafallah AM, Burks SS.   +8 more
europepmc   +1 more source