Results 151 to 160 of about 26,249 (178)

Differences in Dysphagia Between Spinocerebellar Ataxia Type 3 and Type 6

Dysphagia, 2013
Spinocerebellar ataxias (SCAs) are a group of neurodegenerative disorders frequently associated with autosomal dominant inheritance. SCA type 3 (SCA3) and SCA type 6 (SCA6) are the most common forms in Japan as well as the rest of the world. SCA3 affects multiple nervous systems while SCA6 affects mainly the cerebellar system.
Chiharu, Isono, Makito, Hirano, Hikaru, Sakamoto, Shuichi, Ueno, Susumu, Kusunoki, Yusaku, Nakamura   +5 more
openaire   +2 more sources

Cognitive deficits in spinocerebellar ataxia type 1, 2, and 3

Journal of Neurology, 2003
Cognitive impairment was studied in distinct types of spinocerebellar ataxia (SCA): eleven SCA1, 14 SCA2, and 11 SCA3 individuals and 8 age- and IQ- matched controls. All were submitted to a neuropsychological test battery that comprised tests for IQ, attention, executive function, verbal and visuospatial memory.
K, Bürk, C, Globas, S, Bösch, T, Klockgether, C, Zühlke, I, Daum, J, Dichgans   +6 more
openaire   +2 more sources

Clinical correlates of olfactory dysfunction in spinocerebellar ataxia type 3

Parkinsonism & Related Disorders, 2011
Olfactory dysfunction is a very common and early sign in neurodegenerative disorders, but few data are already available in hereditary ataxias. Our aim was to evaluate the sense of smell in patients with molecular-proven spinocerebellar ataxia type 3 (SCA3). Forty-one patients with SCA3 and 46 control subjects were studied.
Braga-Neto, P. UNIFESP, Felicio, A. C. UNIFESP, Pedroso, J. L. UNIFESP, Dutra, L. A. UNIFESP, Bertolucci, P. H. F. UNIFESP, Gabbai, Alberto Alain UNIFESP, Barsottini, O. G. P. UNIFESP   +6 more
openaire   +3 more sources

The parkinsonian phenotype of spinocerebellar ataxia type 3 in a Taiwanese family

Parkinsonism & Related Disorders, 2004
We report a parkinsonian phenotype of spinocerebellar ataxia type 3 (SCA3) in three female sibs from one Taiwanese family, found in a genetic analysis of 60 patients from 49 families with familial parkinsonism. Initially, all three patients presented with early onset resting tremor, rigidity, bradykinesia, and good response to levodopa.
Chin-Song, Lu, Hsiu-Chen, Chang, Pei-Chi, Kuo, Yu-Lun, Liu, Wen-Shiang, Wu, Yi-Hsin, Weng, Tzu-Chen, Yen, Yah-Huei Wu, Chou   +7 more
openaire   +2 more sources

Bilateral vestibulopathy in spinocerebellar ataxia type 3

São Paulo Medical Journal
A 61-year-old man, started having insidious postural oscillations, imbalance and difficulty walking around the age of 30. Between 2013 and 2016, he progressively developed postural hypotension, difficulty to walk, slurred voice, dysarthria, dysphagia, and loss of writing ability.
Raderi Luiz Cardoso dos Santos, Rebecca Ranzani Martins, Fernando Henrique Magri Alves, Emanuelle Roberta da Silva Aquino, Cristiana Borges Pereira   +4 more
openaire   +1 more source

Spinocerebellar ataxia type 3: from pathogenesis to promising therapeutics

Trends in Molecular Medicine
Funded by the European Regional Development Fund (ERDF), through the Centro 2020 Regional Operational Program; through the COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation, and Portuguese national funds via FCT – Fundação para a Ciência e a Tecnologia, under the projects: UIDB/04539/2020, UIDP/04539/2020, LA/P/0058/2020,
Ana Carolina Silva, Miguel Monteiro Lopes, Diana Duarte Lobo, Carina Henriques, Luís Pereira de Almeida, Rui Jorge Nobre   +5 more
openaire   +3 more sources

Spinocerebellar ataxia type 3

2001
S.H. Subramony, Paraminder J.S. Vig
openaire   +1 more source

Spinocerebellar ataxia

Nature Reviews Disease Primers, 2019
Thomas Klockgether, Henry Paulson, Caterina Mariotti   +2 more
exaly   +2 more sources

Cell biology of spinocerebellar ataxia

Journal of Cell Biology, 2012
Harry Orr, Orr Harry T
exaly  

Antisense oligonucleotide therapy for spinocerebellar ataxia type 2

Nature, 2017
C Frank Bennett, Daniel Scoles, Gene Hung   +2 more
exaly