Results 31 to 40 of about 369,855 (297)

Spinor Equations of Smarandache Curves in E3

open access: yesMathematics
This study examines the spinor representations of TN (tangent and normal), NB (normal and binormal), TB (tangent and binormal) and TNB (tangent, normal and binormal)–Smarandache curves in three-dimensional Euclidean space E3.
Zeynep İsabeyoǧlu   +2 more
doaj   +1 more source

A positive energy theorem for AdS solitons

open access: yesPhysics Letters B, 2023
The uncharged AdS4 soliton has been recently shown to be continuously connected to a magnetic, supersymmetric AdS4 soliton within N=8 gauged supergravity.
Andrés Anabalon   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Spinor stochastic resonance [PDF]

open access: yesPhysical Review B, 2015
We report on noise-induced-spin-ordering in a collective quasipaticle system: spinor stochastic resonance. Synergetic interplay of a polarization-modulated signal and a polarization-noise allows us to switch coherently between the two metastable states of a microcavity-polariton spin bistable system.
Abbaspour, H   +4 more
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Localization of spinor fields in higher-dimensional braneworlds

open access: yesJournal of High Energy Physics, 2023
In this paper we investigate the localization of spinor fields in braneworld models by reducing a Dirac spinor in 2n + 2-dimensional spacetime to spinors in 2n dimensions.
Jun-Jie Wan, Yu-Xiao Liu
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Magnetic Ordering in Systems of Identical Particles with an Arbitrary Spin

open access: yesChemosensors, 2019
The Wigner−Eckart theorem is used for considering the collective effects related to ordering spins in systems of identical particles in ferro- and antiferromagnetic electronic systems, as well as magnetic effects that occur in high spin systems ...
Elena Orlenko, Fedor Orlenko
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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