Results 41 to 50 of about 1,961 (171)

Pure sensory stroke caused by a pontine infarct. Clinical, radiological, and physiological features in four patients.

open access: yes, 1994
We conducted this retrospective study to evaluate the clinical, neuroradiological, and neurophysiological findings in patients with pure sensory stroke due to pontine lacuna. Four patients with pontine lacuna, three men and one woman (mean age,
S Shintani, S Tsuruoka, T Shiigai
core   +1 more source

NaV1.7 mRNA and Protein Expression in Resident Neurons of the Human Spinal Dorsal Horn

open access: yesJournal of Comparative Neurology, Volume 534, Issue 5, May 2026.
We identified Nav1.7 mRNA and protein in human spinal cord neurons, a subset of which co‐expressed putative projection neuron markers, TACR1 and GPR83. These neurons relay nociceptive signals from the periphery to the brain. While Nav1.7 loss‐of‐function mutations cause congenital insensitivity to pain, traditionally linked to sensory neurons, our ...
Stephanie Shiers   +9 more
wiley   +1 more source

Dysphagia as the Sole Presentation of Lateral Medullary Syndrome in an Octagerian: A Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Lateral medullary syndrome (LMS) or Wallenberg's syndrome is usually caused by a cerebrovascular accident of the vertebral artery or the posterior inferior cerebellar artery (PICA), leading to damage to the dorsolateral aspects of the medulla oblongata.
Abera Kuma   +5 more
wiley   +1 more source

Electroacupuncture Modulates Multiple Pathways for Neuroprotection and Neurorepair in Ischemic Stroke

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
EA exerts therapeutic effects in ischemic stroke through multiple mechanisms: it alleviates acute injury by suppressing neuroinflammation, excitotoxicity, oxidative stress, apoptosis, pyroptosis, ferroptosis, autophagy dysregulation, and blood–brain barrier disruption, while enhancing cerebral blood flow, angiogenesis, and neurogenesis to support ...
Mingyue Zhao   +8 more
wiley   +1 more source

Brain white matter damage in SCA1 and SCA2. An in vivo study using voxel-based morphometry, histogram analysis of mean diffusivity and tract-based spatial statistics

open access: yes, 2008
BACKGROUND AND PURPOSE: Neurodegeneration in spinocerebellar ataxia type 1(SCA1) and 2(SCA2) is associated with white matter(WM) damage. Voxel-Based Morphometry(VBM), histogram analysis of mean diffusivity(MD) and Tract-Based Spatial Statistics(TBSS ...
SALVATORE, ELENA   +20 more
core   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

open access: yesCatheterization and Cardiovascular Interventions, Volume 107, Issue 4, Page 869-884, March 1, 2026.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet   +4 more
wiley   +1 more source

Sex Differences and Role of Gonadal Hormones on Glutamate Level After Spinal Cord Injury in Rats: A Microdialysis Study

open access: yesBasic and Clinical Neuroscience, 2019
Introduction: Sex differences in outcomes of Spinal Cord Injury (SCI) suggest a sex-hormone-mediated effect on post-SCI pathological events, including glutamate excitotoxicity.
Razieh Samandari   +4 more
doaj  

Non‐Invasive Brain Stimulation in Chronic Pain: Current Evidence, Network Perspectives and Paths to Personalization

open access: yesSensory Neuroscience, Volume 2, Issue 1, March 2026.
Chronic pain reflects maladaptive network interactions across sensory, salience/affective, and descending modulatory pathways. We review evidence for non‐invasive brain stimulation—rTMS, tES, and low‐intensity focused ultrasound—highlighting modest, variable, and often short‐lived analgesic effects under conventional protocols.
Fabian Broecker, Sven Vanneste
wiley   +1 more source

Location and properties of dorsal horn neurons at origin of spinoreticular tract in lumbar enlargement of the rat

open access: yes, 1980
1. Spinoreticular tract neurons at the rat lumbar cord level were identified by antidromic activation following stimulation at mainly pontine and mesencephalic levels. These units, which were found in the dorsal half of the cord, could be separated into
D. Menetrey, J. M. Besson, A. Chaouch
core   +1 more source

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