Results 41 to 50 of about 1,961 (171)
We conducted this retrospective study to evaluate the clinical, neuroradiological, and neurophysiological findings in patients with pure sensory stroke due to pontine lacuna. Four patients with pontine lacuna, three men and one woman (mean age,
S Shintani, S Tsuruoka, T Shiigai
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NaV1.7 mRNA and Protein Expression in Resident Neurons of the Human Spinal Dorsal Horn
We identified Nav1.7 mRNA and protein in human spinal cord neurons, a subset of which co‐expressed putative projection neuron markers, TACR1 and GPR83. These neurons relay nociceptive signals from the periphery to the brain. While Nav1.7 loss‐of‐function mutations cause congenital insensitivity to pain, traditionally linked to sensory neurons, our ...
Stephanie Shiers +9 more
wiley +1 more source
ABSTRACT Lateral medullary syndrome (LMS) or Wallenberg's syndrome is usually caused by a cerebrovascular accident of the vertebral artery or the posterior inferior cerebellar artery (PICA), leading to damage to the dorsolateral aspects of the medulla oblongata.
Abera Kuma +5 more
wiley +1 more source
EA exerts therapeutic effects in ischemic stroke through multiple mechanisms: it alleviates acute injury by suppressing neuroinflammation, excitotoxicity, oxidative stress, apoptosis, pyroptosis, ferroptosis, autophagy dysregulation, and blood–brain barrier disruption, while enhancing cerebral blood flow, angiogenesis, and neurogenesis to support ...
Mingyue Zhao +8 more
wiley +1 more source
BACKGROUND AND PURPOSE: Neurodegeneration in spinocerebellar ataxia type 1(SCA1) and 2(SCA2) is associated with white matter(WM) damage. Voxel-Based Morphometry(VBM), histogram analysis of mean diffusivity(MD) and Tract-Based Spatial Statistics(TBSS ...
SALVATORE, ELENA +20 more
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Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet +4 more
wiley +1 more source
Introduction: Sex differences in outcomes of Spinal Cord Injury (SCI) suggest a sex-hormone-mediated effect on post-SCI pathological events, including glutamate excitotoxicity.
Razieh Samandari +4 more
doaj
Chronic pain reflects maladaptive network interactions across sensory, salience/affective, and descending modulatory pathways. We review evidence for non‐invasive brain stimulation—rTMS, tES, and low‐intensity focused ultrasound—highlighting modest, variable, and often short‐lived analgesic effects under conventional protocols.
Fabian Broecker, Sven Vanneste
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1. Spinoreticular tract neurons at the rat lumbar cord level were identified by antidromic activation following stimulation at mainly pontine and mesencephalic levels. These units, which were found in the dorsal half of the cord, could be separated into
D. Menetrey, J. M. Besson, A. Chaouch
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