Results 21 to 30 of about 1,961 (171)

Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system. [PDF]

, 2000
Targeted expression of foreign genes to the peripheral nervous system is interesting for many applications, including gene therapy of neuromuscular diseases, neuroanatomical studies, and elucidation of mechanisms of axonal flow.
Flechsig, E, Paterna, J C, Glatzel, M, Büeler, H, Klein, M A, Navarro, B, Aguzzi, A; https://orcid.org/   +6 more
core   +1 more source

Radiological and clinical biomarkers in patients with central post stroke pain [PDF]

Romanian Journal of Neurology
Background. Central post-stroke pain (CPSP) occurs following cerebrovascular accidents and is a neuropathic pain syndrome that is characterized by stimulation-independent pain; shooting, burning, or electric shock-like sensation and paresthesia. Multiple
Khaled Eltoukhy, Mohammed Abbas, Ahmad El-Morsy, Omar Kamal Radwan   +3 more
doaj   +1 more source

Facial sensory symptoms in medullary infarcts Sintomas sensitivos na face em infartos medulares

Arquivos de Neuro-Psiquiatria, 2005
OBJECTIVE: To investigate the correlation between facial sensory abnormalities and lesional topography in eight patients with lateral medullary infarcts (LMIs).
Adriana Bastos Conforto, Fábio Iuji Yamamoto, Cláudia da Costa Leite, Milberto Scaff, Suely Kazue Nagahashi Marie   +4 more
doaj   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, Volume 13, Issue 39, 13 July 2026.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Integrating yoga into anatomy and clinical medicine education: A holistic approach to learning

Anatomical Sciences Education, Volume 19, Issue 7, Page 1097-1109, July 2026.
Abstract Anatomical knowledge is fundamental for success in clinical settings. Unfortunately, anatomy education within professional health programs has experienced a continual decrease in contact hours and curricular content over the previous two decades, leading to deficits and potential gaps in anatomical science knowledge.
Dana Rohde, Madeleine E. Norris, Jennifer R. Kinder, Barbie Klein, Derek Harmon   +4 more
wiley   +1 more source

Supraspinal Circuit Mechanisms Underlying Itch Processing

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Peripheral pruriceptive signals ascend from the spinal cord to the brainstem, thalamus, and cortex to encode the sensory features of itch. Parallel projections to limbic and basal ganglia circuits mediate affective and motivational components, including aversion and scratching urge.
Yuncheng Luo, Hao‐Di Tang, Ping Liao, Ruotian Jiang   +3 more
wiley   +1 more source

Neuroimaging Correlates of Post‐Stroke Pain After Ischemic Stroke: Secondary Analysis of the INSPiRE‐TMS Trial

Human Brain Mapping, Volume 47, Issue 10, July 2026.
In 1022 minor ischemic stroke patients, baseline anxiety was associated with new severe pain at 1 year. In the MRI subgroup (N = 391), lesion network mapping implicated a distributed network including the insula, anterior cingulate cortex, and thalamus; Neurosynth decoding showed the highest similarity to pain and nociception terms.
Alina Stegemann, Ana Sofia Rios, Ahmed Khalil, Ulrike Grittner, Uchralt Temuulen, Ramanan Ganeshan, Tim Bastian Braemswig, Andreas Horn, Thomas Ihl, Heinrich J. Audebert, Anna Kufner, Matthias Endres   +11 more
wiley   +1 more source

Pain Pathways and Pain Physiology

, 2018
Pain is a multidimensional sensory experience that is mediated by complex peripheral and central neuroanatomical pathways and mechanisms. Typically, noxious stimuli activate specific peripheral nerve terminals onto Aδ‎ and C nerve fibers that convey pain
Price, Chane, Huq, Zahid, Sarantopoulos, Constantine, Sivanesan, Eellan   +3 more
core   +1 more source