Results 11 to 20 of about 89 (86)

The crossing of the spinothalamic tract [PDF]

open access: yesBrain, 2001
The question whether the spinothalamic and spinoreticular fibres cross the cord transversely or diagonally was investigated in cases of anterolateral cordotomy and in a case of thrombosis of the anterior spinal artery. The pattern of sensory loss following transection of the anterolateral quadrant of the cord consists of a narrow area of decreased ...
P W, Nathan, M, Smith, P, Deacon
openaire   +2 more sources

Thermal Stimulation Changes Diffusivity of the Spinothalamic Tract [PDF]

open access: yesSpine, 2018
Study Design. An experimental study. Objective. This study aimed to investigate task-dependent changes in fractional anisotropy (FA) within the spinal cord during painful stimulation. Summary of Background Data.
Lin, Joanne C.   +2 more
openaire   +2 more sources

Actions of opioids on primate spinothalamic tract neurons [PDF]

open access: yesThe Journal of Neuroscience, 1986
The effects of iontophoretically applied opiates were tested on 24 spinothalamic tract cells in 12 anesthetized monkeys. The drugs used were chosen because of their agonist actions on different classes of opiate receptors (mu, morphine; kappa, dynorphin; delta, methionine enkephalinamide; sigma, N-allylnormetazocine or SKF 10047 and phencyclidine). The
W S, Willcockson   +4 more
openaire   +2 more sources

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, Volume 13, Issue 39, 13 July 2026.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

Integrating yoga into anatomy and clinical medicine education: A holistic approach to learning

open access: yesAnatomical Sciences Education, Volume 19, Issue 7, Page 1097-1109, July 2026.
Abstract Anatomical knowledge is fundamental for success in clinical settings. Unfortunately, anatomy education within professional health programs has experienced a continual decrease in contact hours and curricular content over the previous two decades, leading to deficits and potential gaps in anatomical science knowledge.
Dana Rohde   +4 more
wiley   +1 more source

Supraspinal Circuit Mechanisms Underlying Itch Processing

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Peripheral pruriceptive signals ascend from the spinal cord to the brainstem, thalamus, and cortex to encode the sensory features of itch. Parallel projections to limbic and basal ganglia circuits mediate affective and motivational components, including aversion and scratching urge.
Yuncheng Luo   +3 more
wiley   +1 more source

Neuroimaging Correlates of Post‐Stroke Pain After Ischemic Stroke: Secondary Analysis of the INSPiRE‐TMS Trial

open access: yesHuman Brain Mapping, Volume 47, Issue 10, July 2026.
In 1022 minor ischemic stroke patients, baseline anxiety was associated with new severe pain at 1 year. In the MRI subgroup (N = 391), lesion network mapping implicated a distributed network including the insula, anterior cingulate cortex, and thalamus; Neurosynth decoding showed the highest similarity to pain and nociception terms.
Alina Stegemann   +11 more
wiley   +1 more source

17. Cancer Pain: Part I: Cordotomy for Unilateral Pain due to Cancer

open access: yesPain Practice, Volume 26, Issue 6, July 2026.
ABSTRACT Introduction Despite advancements in pharmacological and intrathecal treatment of oncological pain, it remains a significant challenge, affecting 44.5% of patients with cancer, with 30.6% experiencing moderate‐to‐severe pain. Methods This scoping review provides a summary of the literature from 2016 to 2024, focusing on percutaneous cordotomy ...
Bregje Huisman   +7 more
wiley   +1 more source

Outcomes of 87 small‐breed dogs surgically treated for Chiari‐like malformation and syringomyelia

open access: yesVeterinary Surgery, Volume 55, Issue 5, Page 929-941, July 2026.
Abstract Objective To report the outcomes of titanium mesh (TM) cranioplasty without polymethylmethacrylate (PMMA), incorporating a deliberate gap between the foramen magnum decompression (FMD) surface and the TM, in small‐breed dogs with Chiari‐like malformation and syringomyelia (CM/SM). Study design Retrospective clinical study.
Sung Su Park, Ji Young Park, Ho Jae Han
wiley   +1 more source

From three‐dimensional culture to translational modeling: Human spinal cord organoids as an emerging precision platform for neurotrauma research

open access: yesBrain‐X, Volume 4, Issue 2, June 2026.
Human pluripotent stem cell (hPSC)‐derived spinal cord organoids (SCOs) provide a controllable three‐dimensional platform to examine regional patterning, cellular composition, injury‐associated responses, and functional circuitry. These models can support mechanistic studies, drug screening, and assessment of bioengineered repair approaches ...
Shi Lv   +6 more
wiley   +1 more source

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