Results 91 to 100 of about 695,293 (298)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Mongolskie oblicza postpamięci

open access: yesPoliteja, 2017
The Faces of Mongolian Postmemory This article applies the concept of postmemory to demonstrate the relation of modern Mongolia to its own past and history.
Celina Strzelecka
doaj   +1 more source

Wave Propagation in 1-D Spiral geometry [PDF]

open access: yes, 2014
In this article, we investigate the wave equation in spiral geometry and study the modes of vibrations of a one-dimensional (1-D) string in spiral shape.
Chatterjee, Deep, Nayak, Rajesh K.
core  

Spiral Waves in Driven Dusty Plasma Medium: Generalized Hydrodynamic Fluid Description

open access: yes, 2017
Spiral waves are observed in many natural phenomena. They have been extensively represented by the mathematical FitzHugh-Nagumo (FHN) model [Barkley et al., Phys. Rev. A 42, 2489 (1990)] of excitable media.
Das, Amita   +2 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Driving unit design and motion analysis for a spiral propulsion mechanism in wetlands

open access: yesMechanical Engineering Journal, 2014
Environmental problems related to wetlands have attracted strong concern around the world during past decades. Mobile mechanisms of many kinds have been developed to satisfy demands of environmental investigation of wetlands.
Qunpo LIU   +4 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

John Barth's "Dunyazadiad": A Postmodern Reading of an Eastern Frame

open access: yesآداب الكوفة, 2017
The frame-tale technique is one of the most ancient narrative techniques, its roots go back to the oral tradition. It refers to a set of embedded stories which are encircled by a larger framework, hence creating a hierarchical pattern of stories within ...
Qassim Salman Sarhan, Marwa Ali Al-Shara
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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