Results 61 to 70 of about 233,450 (266)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Quantum spin spiral ground state of the ferrimagnetic sawtooth chain
, 2022 The publication contains the dataset which is a supplemental material for the paper "Quantum spin spiral ground state of the ferrimagnetic sawtooth chain" (arXiv preprint arXiv:2207.08273).
Rausch, Roman
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Needleless electrospinning of uniform nanofibers using spiral coil spinnerets [PDF]
, 2012 Polyvinyl alcohol nanofibers were prepared by a needleless electrospinning technique using a rotating spiral wire coil as spinneret. The influences of coil dimension (e.g., coil length, coil diameter, spiral distance, and wire diameter) and operating ...
Lin, Tong +3 more
core +1 more source
The Morphological Aberrations of Cystic Duct and its Clinical Significance: A Gross Anatomical Study
International Journal of Anatomy Radiology and Surgery, 2018 Introduction: The Cystic Duct (CD) serves as a thorough fare for transport of bile to and away from the gallbladder. It is about 2-4 cm in length and 1-5 mm in diameter, and joins the Common Hepatic Duct (CHD) at its right lateral aspect, in the ...
Jaba Rajguru, Mitesh Dave
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Wheels up: Spiral progression pedagogy towards creative movers using wheels [PDF]
, 2023 This study explored a trailblazing creative means for Physical Education (PE) preservice teachers (PSTs) to explore movement: agility, balance and coordination by embodying a reflective approach to a series of practical challenges.
Howells, K., Murray, A.M.
core
Computer, 2020 Computer has published many important articles, but few are as important or had such a lasting impact as Barry Boehm's classic article on software engineering. Barry Boehm's article, "A Spiral Model of Software I Development and Enhancement"' is a classic in the fullest sense of the word.
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source