Results 71 to 80 of about 695,293 (298)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Design and Construction of a 500–800 MHz Square Spiral Dipole Microstrip Antenna Structure

Journal of Electrical Engineering and Computer
An antenna can be used to detect an object. The dimensions of the antenna also affect the working frequency, the smaller dimensions, the higher the working frequency and the closer the antenna range to radiate waves.
Arif Milando Setiawan
doaj   +1 more source

Instabilities of Spiral Shocks I: Onset of Wiggle Instability and its Mechanism

, 2003
We found that loosely wound spiral shocks in an isothermal gas disk caused by a non-axisymmetric potential are hydrodynamically unstable, if the shocks are strong enough.
Athanassoula, Balbus, Balbus, Balsara, Benz, Chandrasekhar, Dwarkadas, Elmegreen, Elmegreen, Fukuda, Fukuda, Fumimoto, Hernquist, Ishibashi, Jin Koda, Johns, Keiichi Wada, Kim, Koda, Kudoh, Lin, Liou, Liou, Lubow, Mishurov, Monaghan, Nelson, Piner, Roberts, Sawa, Scoville, Shu, Shu, Spitzer, Thomas, Tomisaka, Van Leer, Wada, Wada, Wada, Wada, Wada, Wada, Woodward, Woodward, Yabe   +45 more
core   +3 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Numerical Analysis of Three-Dimensional Proton Exchange Membrane Fuel Cell with Spiral Channels [PDF]

Iranian Journal of Chemistry & Chemical Engineering
We introduce a 3D methodology based on the Finite Volume Method to solve the governing equations of the Proton Exchange Membrane Fuel Cell with a spiral gas channel design. These equations were evaluated in both the anode and cathode gas channels.
Sepehr Senfi, Ata Chitsaz, Abdolsalam Ebrahimpour, Roghayyeh Motallebzadeh   +3 more
doaj   +1 more source

TEXTILE PATTERNS FOR INTERIOR DESIGN WITH THREE-DIMENSIONAL SPIRALS [PDF]

Annals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2023
Three-dimensional (3D) spirals are fascinating geometric shapes that are used in a variety of applications, such as textile fabric pattern and texture design, architecture, art, and engineering.
ILIEVA Julieta, INDRIE Liliana, STOYKOVA Vanya, ZLATEV Zlatin   +3 more
doaj  

Spiral Waves in Media with Complex Excitable Dynamics

, 1999
The structure of spiral waves is investigated in super-excitable reaction-diffusion systems where the local dynamics exhibits multi-looped phase space trajectories.
ANDREI GORYACHEV, Barkley D., Goryachev A., RAYMOND KAPRAL, Tyson J., Winfree A.   +5 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source