Results 41 to 50 of about 109,816 (295)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Stellar dynamics around transient co-rotating spiral arms
EPJ Web of Conferences, 2012 Spiral density wave theory attempts to describe the spiral pattern in spiral galaxies in terms of a long-lived wave structure with a constant pattern speed in order to avoid the winding dilemma.
Cropper M., Grand R.J.J., Kawata D.
doaj +1 more source
Stellar Motion around Spiral Arms: Gaia Mock Data [PDF]
, 2014 We compare the stellar motion around a spiral arm created in two different scenarios, transient/co-rotating spiral arms and density-wave-like spiral arms.
Cropper, M. +5 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Stiffness estimation of planar spiral spring based on Gaussian process regression
Scientific Reports, 2022 Planar spiral spring is important for the dimensional miniaturisation of motor-based elastic actuators. However, when the stiffness calculation of the spring arm is based on simple beam bending theory, the results possess substantial errors compared with
Jingjing Liu +6 more
doaj +1 more source
The dynamics of spiral arms in pure stellar disks
, 2011 It has been believed that spirals in pure stellar disks, especially the ones spontaneously formed, decay in several galactic rotations due to the increase of stellar velocity dispersions.
Baba +22 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Star Formation and Magnetic Field Amplification due to Galactic Spirals
The Astrophysical JournalWe use global MHD galaxy simulations to investigate the effects of spiral arms on the evolution of magnetic fields and star formation within a self-regulated interstellar medium.
Hector Robinson +3 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
A New Statistical Analysis of the Morphology of Spiral Galaxies
The Astronomical JournalMorphology is the starting point for understanding galaxies. Elmegreen et al. classified spiral galaxies into flocculent, multiple-arm, and grand-design galaxies based on the regularity of their spiral arm structure.
Junye Wei +6 more
doaj +1 more source