Results 71 to 80 of about 109,364 (298)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

The collective origin of spiral structures in disk galaxies

EPJ Web of Conferences, 2012
After almost fifty years the origin of spiral arms in disk galaxies remains one of the major unsolved problems in astrophysics. Recent attempts have indicated that substructures in the dark matter halos of galaxies could induce spiral patterns in disks ...
Hernquist L., Vogelsberger M., D’Onghia E.   +2 more
doaj   +1 more source

What Does the Milky Way Look Like?

The Astrophysical Journal, 2023
In spite of much work, the overall spiral structure morphology of the Milky Way remains somewhat uncertain. In the last two decades, accurate distance measurements have provided us with an opportunity to solve this issue.
Y. Xu, C. J. Hao, D. J. Liu, Z. H. Lin, S. B. Bian, L. G. Hou, J. J. Li, Y. J. Li   +7 more
doaj   +1 more source

Spiral arm formation mechanisms: Spiral Structure in Barred galaxies. Observational constraints to spiral arm formation mechanisms

, 2019
A method which we have developed for determining corotation radii, has allowed us to map in detail the radial resonant structures of barred spiral galaxies. Here we have combined this information with new determinations of the bar strength and the pitch angle of the innermost segment of the spiral arms to find relationships between these parameters of ...
Font, Joan, Beckman, John E., James, Phil A., Patsis, Panos A.   +3 more
openaire   +2 more sources

Magnetic Fields in Spiral Arms.

The Astrophysical Journal, 1953
In this paper two independent methods are described for estimating the magnetic field in the spiral arm in which we are located. The first method is based on an interpretation of the dispersion (of the order of 10° ) in the observed planes of polarization of the light of the distant stars; it leads to an estimate of H = 7.2 X 10 -6 gauss.
S. Chandrasekhar, E. Fermi
openaire   +1 more source

The Myth of the Molecular Ring

, 2012
We investigate the structure of the Milky Way by determining how features in a spatial map correspond to CO features in a velocity map. We examine structures including logarithmic spiral arms, a ring and a bar.
Burkert, A., Dobbs, C. L.
core   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

JWST Reveals a Surprisingly High Fraction of Galaxies Being Spiral-like at 0.5 ≤ z ≤ 4

The Astrophysical Journal Letters
Spiral arms are one of the most important features used to classify the morphology of local galaxies. The cosmic epoch when spiral arms first appeared contains essential clues to the evolution of disk galaxies.
Vicki Kuhn, Yicheng Guo, Alec Martin, Julianna Bayless, Ellie Gates, AJ Puleo   +5 more
doaj   +1 more source

Galaxy Zoo and sparcfire: constraints on spiral arm formation mechanisms from spiral arm number and pitch angles [PDF]

Monthly Notices of the Royal Astronomical Society, 2017
In this paper we study the morphological properties of spiral galaxies, including measurements of spiral arm number and pitch angle. Using Galaxy Zoo 2, a stellar mass-complete sample of 6,222 SDSS spiral galaxies is selected. We use the machine vision algorithm SpArcFiRe to identify spiral arm features and measure their associated geometries.
Ross E. Hart, Steven P. Bamford, Wayne B. Hayes, Carolin N. Cardamone, William C. Keel, Sandor J. Kruk, Chris J. Lintott, Karen L. Masters, Brooke D. Simmons, Rebecca J. Smethurst   +9 more
openaire   +7 more sources

Controlled Movement of Soft Actuators using Multi‐Responsive Microgel Arrays and Microcirculatory Systems

Advanced Functional Materials, EarlyView.
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang, Brennan P. Watts, Stephen A. Morin   +2 more
wiley   +1 more source