Results 61 to 70 of about 23,483 (241)

Human Leukocyte Antigens in Pregnancy and Preeclampsia

Frontiers in Genetics, 2022
Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which includes underlying maternal cardiovascular disease, deficient spiral artery remodeling during placenta development, and inflammatory immune responses at the maternal-
Omonigho Aisagbonhi, Gerald P. Morris
doaj   +1 more source

The burden of intracranial atherosclerosis on cerebral small vessel disease: A community cohort study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah, Heng Du, Wenjie Yang, Huixing Zeng, Jason Tsz Lok Chan, Michael Lung Cheung Lo, Xiangyan Chen   +6 more
wiley   +1 more source

Roles of HLA-G in the Maternal-Fetal Immune Microenvironment

Frontiers in Immunology, 2020
During pregnancy, the maternal uterus and fetus form a special microenvironment at the maternal-fetal interface to support fetal development. Extravillous trophoblasts (EVTs), differentiated from the fetus, invade into the decidua and interact with ...
Xiuxiu Xu, Xiuxiu Xu, Yonggang Zhou, Yonggang Zhou, Yonggang Zhou, Haiming Wei, Haiming Wei   +6 more
doaj   +1 more source

Altered placental expression of genes related to Vitamin D Metabolism and their correlation with spiral artery remodeling in Preeclamptic Women [PDF]

Background: Several studies reveals the correlation of preeclampsia (PE) with low vitamin D (VD) level due to disturbed trophoblast invasion and failure of spiral artery remodeling.
Goswami, Pushpa, Gul, Fahmida, Memon, Samreen, Ujjan, Ikram Din   +3 more
core   +2 more sources

Interleukin-11 alters placentation and causes preeclampsia features in mice [PDF]

, 2015
Preeclampsia is an insidious disease, unique to humans, affecting ∼8% of pregnancies. There are no early detection tests or pharmacological treatments. Impaired placentation is widely accepted to contribute to the pathogenesis.
Cuman, Carly, Dimitriadis, Evdokia, Koga, Kaori, Menkhorst, Ellen, Nagai, Miwako, Rainczuk, Katarzyna, Simmons, David, Van Sinderen, Michelle, Winship, Amy L., Yap, Joanne, Young, Morag J., Zhang, Jian-Guo   +11 more
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Mechanical Metamaterials for Bioengineering: In Vitro, Wearable, and Implantable Applications

Advanced Engineering Materials, Volume 27, Issue 7, April 2025.
Mechanical metamaterials with engineered architectures exhibit properties that differ from and greatly surpass those of their constituent bulk materials. This review summarizes the applications of mechanical metamaterials in bioengineering, focusing on advances in the last 5 years.
Madihah Kazim, Aniket Pal, Debkalpa Goswami   +2 more
wiley   +1 more source

Corin: A Key Mediator in Sodium Homeostasis, Vascular Remodeling, and Heart Failure

Biology, 2022
Atrial natriuretic peptide (ANP) is a crucial element of the cardiac endocrine function that promotes natriuresis, diuresis, and vasodilation, thereby protecting normal blood pressure and cardiac function. Corin is a type II transmembrane serine protease
Xianrui Zhang, Xiabing Gu, Yikai Zhang, Ningzheng Dong, Qingyu Wu   +4 more
doaj   +1 more source

Initial Stress Symmetry and Applications in Elasticity [PDF]

, 2015
An initial stress within a solid can arise to support external loads or from processes such as thermal expansion in inert matter or growth and remodelling in living materials. For this reason it is useful to develop a mechanical framework of initially stressed solids irrespective of how this stress formed.
arxiv   +1 more source

More ATP Does Not Equal More Contractility: Power And Remodelling In Reconstituted Actomyosin [PDF]

arXiv, 2021
The cytoskeletal component actomyosin is a canonical example of active matter since the powerstroke cycle locally converts chemical energy in the form of adenoside triphosphate (ATP) into mechanical work for remodelling. Observing myosin II minifilaments as they remodel actin {\it in vitro}, we now report that: at high concentrations of ATP, myosin ...
arxiv