A Chiral Saddle‐Shaped Nanographene With Two Heptagon‐Embedded [4]Helicenes
We present a novel synthetic strategy toward a chiral saddle‐shaped nanographene (cSNG) via a two‐step oxidation of a prochiral anthracene precursor. The Scholl‐type oxidation first yields a key intermediate with sp3‐defect heptagons, and subsequent oxidative dehydrogenation affords fully conjugated cSNG.
Felix Trautner +11 more
wiley +1 more source
Fine-Tuning a Transformer Model for METTL3 Lead Optimization. [PDF]
Matter CM, Caflisch A.
europepmc +1 more source
An Fe(II)-catalyzed synthesis of spiro[indoline-3,2'-pyrrolidine] derivatives. [PDF]
Gradova EV +6 more
europepmc +1 more source
Regioselective synthesis of novel spiro-isoxazolines congeners as antimicrobial agents: <i>in vitro</i> and <i>in-silico</i> assessments. [PDF]
Bouzammit R +13 more
europepmc +1 more source
Adamantane-based inhibitors of the influenza A M2 proton channel: structure-based design, biological evaluation, and synthetic approaches. [PDF]
Stampolaki M +3 more
europepmc +1 more source
Diastereodivergent and Enantioselective Organocatalytic Synthesis of Spiro-Fused Coumarins via [4+2] Cycloadditions. [PDF]
Hidalgo-León R +5 more
europepmc +1 more source
Structural diversity and therapeutic potential of phenanthrenes from the <i>Dendrobium</i> genus: a comprehensive review (1987-2025). [PDF]
Jian J +8 more
europepmc +1 more source
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AbstractA Meisenheimer compound has been prepared by the action of a base on 1‐(2′‐hydroxyethoxy)‐2,4,6‐trinitrobenzene. The structure contains a 1,3‐dioxolane ring linked to the six membered ring containing the pentadienate system by a common carbon atom.
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