Membrane-forming phospholipids allosterically modulate native-state prolyl isomerization in a CNG channel. [PDF]
Abstract Ion channel activity is intricately linked to the surrounding lipid environment, yet the molecular effects of lipid‐mediated regulation remain largely understudied. Here, we show that membrane‐forming phospholipids, which are known to modulate the activity of the cyclic nucleotide‐gated channel SthK from Spirochaeta thermophila, exhibit ...
Newton AJ +3 more
europepmc +2 more sources
Mesenchymal Stem Cells Reduce Inflammation in a Mouse Model of Lyme Arthritis. [PDF]
Lyme disease (LD), a zoonotic infectious disease caused by Borrelia burgdorferi (B. burgdorferi), can affect various organs, including the skin, heart, nervous system, and joints. Lyme arthritis (LA) is the most common and severe late‐stage presentation of LD, often presenting with intermittent joint swelling and pain.
Ma W +23 more
europepmc +2 more sources
Bacterial symbionts of the precious coral Corallium rubrum are differentially distributed across colony‐specific compartments and differ among colormorphs [PDF]
The distribution and functions of the symbiotic microbes of the precious coral Corallium rubrum are unknown. We optimised coral dissection protocols by using RNAlater, and employed 16S rRNA metabarcoding to characterise the microbiota in different compartments (polyps, coenenchyme, skeleton) and in three colormorphs (red, pink, white).
van de Water J +2 more
europepmc +2 more sources
Chemotaxis in Spirochaeta aurantia [PDF]
Cell of Spirochaeta aurantia M1 suspended in isotropic buffer solution swam in nearly straight lines and appeared to spin around their longitudinal axis. Occasionally, cells stopped and flexed, and then resumed translational motility, usually in a different direction. The average cell velocity was 26 micron/s.
E P, Greenberg, E, Canale-Parola
openaire +2 more sources
A possible unique ecosystem in the endoglacial hypersaline brines in Antarctica
Here, we present the results related to a new unique terrestrial ecosystem found in an englacial hypersaline brine found in Northern Victoria Land (Antarctica).
M. Guglielmin +10 more
doaj +1 more source
Lyme Disease and New Molecular Biological Detection Methods [PDF]
Molecular biology plays an important role in understanding the structures, functions and internal controls within each cell. All this can be used to diagnose the diseases, effectively target new medicines and better understand cellular physiology.
Ali Choopani +3 more
doaj +1 more source
Description of Treponema azotonutricium sp. nov. and Treponema primitia sp. nov., the First Spirochetes Isolated from Termite Guts [PDF]
Long after their original discovery, termite gut spirochetes were recently isolated in pure culture for the first time. They revealed metabolic capabilities hitherto unknown in the Spirochaetes division of the Bacteria, i.e., H2 plus CO2 acetogenesis (J.
Breznak, John A. +2 more
core +1 more source
Chemotaxis mutants of Spirochaeta aurantia [PDF]
Five Spirochaeta aurantia chemotaxis mutants were isolated. One mutant (the che-101 mutant) never reversed, one (the che-200 mutant) flexed predominantly, two (the che-300 and che-400-1 mutants) exhibited elevated reversal frequencies, and one (the che-400 mutant) exhibited chemotactically unstimulated behavior similar to that of the wild-type strain ...
K, Fosnaugh, E P, Greenberg
openaire +2 more sources
Borreliae Part 1: Borrelia Lyme Group and Echidna-Reptile Group
Borreliae are divided into three groups, namely the Lyme group (LG), the Echidna-Reptile group (REPG) and the Relapsing Fever group (RFG). Currently, only Borrelia of the Lyme and RF groups (not all) cause infection in humans.
Giusto Trevisan +7 more
doaj +1 more source
Complete genome sequence and description of Salinispira pacifica gen. nov., sp. nov., a novel spirochaete isolated form a hypersaline microbial mat [PDF]
During a study of the anaerobic microbial community of a lithifying hypersaline microbial mat of Lake 21 on the Kiritimati atoll (Kiribati Republic, Central Pacific) strain L21-RPul-D2(T) was isolated.
Ben Hania, Wajdi +8 more
core +3 more sources

