Results 91 to 100 of about 93,359 (239)

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng   +3 more
wiley   +1 more source

Relationship Between Bronchodilator Reversibility and Spirometry Response to Dupilumab in Type 2 High Uncontrolled Severe Asthma

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig   +4 more
wiley   +1 more source

Association between lung function and sleep disorder symptoms in a community‐based multi‐site case‐finding study

open access: yesJournal of Sleep Research, Volume 34, Issue 3, June 2025.
Summary Obstructive airway disease is associated with sleep disturbances. We aimed to assess the relationship between lung function and sleep disorder symptoms using cross‐sectionally collected data between March 2017 and August 2021 from the Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma Population study, a prospective community‐based ...
Rosetta Mazzola   +20 more
wiley   +1 more source

Evaluation of Small Airways Dysfunction With Dupilumab Using Airway Oscillometry in Uncontrolled Severe Asthma

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 264-266, March 2025.
Kirsten E. Stewart   +3 more
wiley   +1 more source

Heterogeneity of reduced FEV1 in early adulthood: A looking forward, looking backwards analysis

open access: yesRespirology, Volume 30, Issue 4, Page 326-334, April 2025.
Abstract Background Some individuals never achieve normal peak FEV1 in early adulthood. It is unknown if this is due to airflow limitation and/or lung restriction. Methods To investigate this, we: (1) looked forward in 19,791 participants in the Dutch Lifelines general population cohort aged 25–35 years with 5‐year follow‐up; and (2) looked backwards ...
Nuria Olvera   +8 more
wiley   +1 more source

Longitudinal Study of Fractional Exhaled Nitric Oxide (FeNO) and Spirometric Indices in Trainee Bakers and Confectioners

open access: yes
Clinical &Experimental Allergy, EarlyView.
Gina‐Maria Klaut   +7 more
wiley   +1 more source

Dynapenia and Sarcopenia as Risk Factors for Mortality in Interstitial Lung Disease

open access: yesRespirology, Volume 30, Issue 5, Page 424-434, May 2025.
ILD patients had a higher prevalence of body composition alterations, among them dynapenia and sarcopenia; these are independent risks for mortality. Pulmonary rehabilitation, including nutritional treatment, should be part of the routine management of this population to improve nutritional status and delay the skeletal muscle disorder.
Alan Aldair Ibarra‐Fernández   +11 more
wiley   +1 more source

A Two‐Staged, Risk‐Stratified Strategy Combining FEV1/FEV6 and COPD Diagnostic Questionnaire Acts as an Accurate and Cost‐Effective COPD Case‐Finding Method

open access: yesRespirology, EarlyView.
ABSTRACT Background and Objective Symptom‐based questionnaires and handheld lung function devices are widely used for COPD case finding, but the optimal combination remains unclear. This study aimed to compare the diagnostic accuracy (DA) of various combinations of handheld lung function devices and questionnaires and develop a COPD case‐finding ...
Po‐Chun Lo   +5 more
wiley   +1 more source

Respiratory Muscle Strength as a Predictor of Exacerbations in Patients With Chronic Obstructive Pulmonary Disease

open access: yesRespirology, Volume 30, Issue 5, Page 408-416, May 2025.
Evaluation of respiratory muscle function is recommended for patients with COPD. Our results suggest that lower respiratory muscle strength is associated with an increased risk of exacerbations. Respiratory muscle function could serve as a marker of disease status and early prognosis in COPD.
Yuichiro Furukawa   +11 more
wiley   +1 more source

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