Results 101 to 110 of about 93,359 (239)

Level of Eosinophil Cationic Protein in Sputum of Chemical Warfare Victims [PDF]

Objective(s) Considering fair response to inhaled corticosteroids and reports of severe air way hyper responsiveness in chemical warfare victims (CWV), a role for eosinophilic inflammation (i.e. asthma) was postulated.
توحیدی, محمد, جعفريان, امير حسين, خاكزاد, محمد رضا, خواجه دلوئی, محمد, عطاران, داود, قبادی مراللو, حسن, محمدزاده لاری, شهرزاد, مير صدرائی, مجيد   +7 more
core  

Functional Lung Imaging Identifies Peripheral Ventilation Changes in ꞵ‐ENaC Mice

Respirology, Volume 30, Issue 4, Page 335-345, April 2025.
β‐ENaC‐Tg mice have previously been shown to exhibit muco‐obstructive disease and emphysema. This study analysed lung function in β‐ENaC‐Tg mice using XV functional imaging and flexiVent assessments. XV enabled ventilation defects to be identified and localised, and the flexiVent comfirmed increased lung compliance and reduced tissue elastance ...
Nicole Reyne, Ronan Smith, Patricia Cmielewski, Nina Eikelis, Kris Nilsen, Jennie Louise, Julia Duerr, Marcus A. Mall, Mark Lawrence, David Parsons, Martin Donnelley   +10 more
wiley   +1 more source

Treatable Trait Guided Asthma Management: A Feasibility Study

Respirology, EarlyView.
ABSTRACT Background and Objectives Treatable trait‐based personalised medicine improves outcomes in severe asthma clinics. We assessed the feasibility of a randomised controlled trial (RCT) of protocolised treatable trait‐guided asthma management in patients not under a severe asthma clinic. Methods Ten week single‐group cohort study.
James Fingleton, Rob McLachlan, Jenny Sparks, Richard Beasley, Alvar Agustí, Peter G. Gibson, Ian D. Pavord, Jo Hardy, Mark Weatherall, Allie Eathorne, Vanessa M. McDonald, the Treatable Traits Study Group, James Fingleton, Vanessa M. McDonald, Jo Hardy, Rob McLachlan, Peter G. Gibson, Ian D. Pavord, Alvar Agusti, Mark Weatherall, Richard Beasley, Augustus Anderson, Luisa Diputado, Allie Eathorne, James Fingleton, James Gilchrist, Jo Hardy, Mark Holliday, Kyley Kerse, John Martindale, Rob McLachlan, Nick Shortt, Jenny Sparks, Vanessa McDonald, Peter Gibson, Jasminka Nikolajevic‐Sarunac, Amber Smith, Paola Urroz   +37 more
wiley   +1 more source

Unlocking Asthma Remission: Key Insights From an Expert Roundtable Discussion

Respirology, EarlyView.
ABSTRACT Treatment targets in severe asthma have evolved towards a remission‐focused paradigm guided by precision medicine. This novel concept requires a shift from evaluating the efficacy of therapies based on a single outcome at a single time point to an outcome that captures the complexity of asthma remission involving several domains assessed over ...
Dennis Thomas, Hayley Lewthwaite, Peter G. Gibson, Eleanor Majellano, Vanessa Clark, Michael Fricker, Yuto Hamada, Gary P. Anderson, Vibeke Backer, Philip Bardin, Richard Beasley, Jimmy Chien, Claude S. Farah, John Harrington, Erin Harvey, Mark Hew, Anne E. Holland, Christine Jenkins, Constance H. Katelaris, Gregory Katsoulotos, Kirsty Murray, Matthew Peters, Rejoy Thomas, Katrina Tonga, John W. Upham, Peter Wark, Vanessa M. McDonald   +26 more
wiley   +1 more source

High Flow Nasal Oxygen and Low Flow Oxygen Are Equally Effective in Providing Oxygenation During Bronchoscopy Under Conscious Sedation: A Randomised Controlled Trial

Respirology, EarlyView.
ABSTRACT Background and Objective Oxygen desaturations and hypoxaemia are common during bronchoscopy despite the use of conventional low flow oxygen (LFO). Some researchers suggest high flow nasal oxygen (HFNO) may improve oxygenation in patients undergoing bronchoscopy; however, trials have varied widely in their methodology and patient population ...
Georgia Burton, Paul Kelly, Brooke Carroll, Chris Frampton, Lutz Beckert   +4 more
wiley   +1 more source

Inspiratory Muscle Training on Exercise Capacity, Dyspnoea and Health Status in Pulmonary Hypertension: A Randomised Controlled Trial

Respirology, EarlyView.
ABSTRACT Background and Objective To evaluate the effects of a high‐intensity inspiratory muscle training on respiratory muscle strength, exercise capacity, dyspnoea, and health‐related quality of life (HRQL) in patients with pulmonary hypertension (PH). Methods Single‐blinded, randomised controlled trial 35 women with clinically stable PH (subgroups 1
Fabrício Farias da Fontoura, Gabriela Roncato, Gisela Martina Bohns Meyer, Cássia da Luz Goulart, Fernanda Brum Spilimbergo, Gerson Cipriano Junior, Marilia Gabriela Bernadeli, Katya Rigatto, Danilo Cortozi Berton   +8 more
wiley   +1 more source

On the 2019 Spirometry Statement [PDF]

American Journal of Respiratory and Critical Care Medicine, 2020
openaire   +2 more sources

Contemporary Concise Review 2024: Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
SUMMARY OF KEY POINTS Non‐smoking COPD is common in LMICs, especially in women. Biomass fuel and air pollution are major risk factors with distinct pathophysiology. The ‘eosinophilic’ endotype in COPD is biologically distinct from asthma. PRISm, FEV1/FVC Z‐scores, and quantitative CT improve early COPD detection.
Sarita Thawanaphong, Parameswaran Nair
wiley   +1 more source

Aspergillus After Lung Transplantation: Prophylaxis, Risk Factors, and the Impact on Chronic Lung Allograft Dysfunction

Transplant Infectious Disease, EarlyView.
Out of 274 lung transplant (LTx) patients, 89 (32%) developed invasive aspergillosis IA. Factors associated with IA were mycophenolate mofetil use, airway stenosis, Aspergillus cultured pre‐LTx, chronic lung allograft dysfunction (CLAD), and acute rejection. The role of nebulized amphotericin B and statins for prevention of IA remains unclear. ABSTRACT
Johanna P. van Gemert, Ger Jan Fleurke, Onno W. Akkerman, C. Tji. Gan, Willie N. Steenhuis, Huib A. M. Kerstjens, Erik A. M. Verschuuren, Douwe F. Postma   +7 more
wiley   +1 more source

Setting sail for Paris 2024: Retrospective analysis of world‐class ILCA 7 Olympic sailors’ cardiorespiratory fitness (2015–2020)

Experimental Physiology, EarlyView.
Abstract The aim of this retrospective analysis was to provide a more comprehensive understanding of the cardiorespiratory profile of world‐class ILCA‐7 sailors (n = 3, all males), through a longitudinal evaluation offering real‐world data on physiological profile and exercise intensity domains. The cardiopulmonary exercise testing (CPET) was performed
Damir Zubac, Zoran Valić, Vladimir Ivančev   +2 more
wiley   +1 more source