Results 31 to 40 of about 6,733 (210)

The association between spirometry measurement quality, cognitive function, and mortality

Archives of Public Health
Background Population studies that assess lung function usually exclude results of individuals with poor-quality measurements, which often means excluding many subjects.
Consuelo Quispe-Haro, Tatyana Court, Magdalena Kozela, Abdonas Tamosiunas, Nadezda Capkova, Hynek Pikhart, Martin Bobák   +6 more
doaj   +1 more source

Small airway function in obese individuals with self-reported asthma

ERJ Open Research, 2020
Diagnosis of asthma in obese individuals frequently relies on clinical history, as airflow by spirometry may remain normal. This study hypothesised that obese subjects with self-reported asthma and normal spirometry will demonstrate distinct clinical ...
Beno W. Oppenheimer, Roberta M. Goldring, Israa Soghier, David Smith, Manish Parikh, Kenneth I. Berger   +5 more
doaj   +1 more source

Lung Ultrasound for the Detection of Radiologic Progression of Interstitial Lung Abnormalities in Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Interstitial lung disease (ILD) is an important extra‐articular manifestation of rheumatoid arthritis (RA) associated with high mortality and morbidity. Lung ultrasonography (LUS) has recently emerged as a possible screening tool. We assessed the role of LUS in monitoring radiologic progression and the development of new interstitial lung ...
Marie Vermant, Valerie Van Ballaer, Joseph Jacob, Tine Follet, Ryoko Egashira, Kenny Anseele, Heleen Cypers, Laurens J. De Sadeleer, Nico De Crem, Tinne Goos, Barbara Neerinckx, Veerle Taelman, Nathalie Veyt, Alexandros Kalkanis, Patrick Verschueren, Wim A. Wuyts   +15 more
wiley   +1 more source

Feasibility, quality and added value of unsupervised at-home spirometry in primary care

npj Primary Care Respiratory Medicine
At-home spirometry could provide added value for the diagnosis and monitoring of obstructive pulmonary disease in primary care. However, it is unknown whether implementation in a real-world setting is practicable and produces good quality spirometry.
T. A. le Rütte, M. Kerkhof, Y. H. Gerritsma, M. M. G. Driessen-Roelfszema, L. van den Bemt, J. W. M. Muris, R. A. Riemersma, H. Sandelowsky, B. Stridh, J. W. H. Kocks   +9 more
doaj   +1 more source

Applying spirometry phenotypes to a longitudinal cohort born very preterm

BMJ Open Respiratory Research
Background To better characterise prematurity-associated lung disease, adult spirometry phenotype classifications (obstructive lung disease, preserved ratio impaired spirometry and dysanapsis) have been applied to children born preterm. It is unknown how
Sanja Stanojevic, Shannon J Simpson, Tiffany K Bradshaw   +2 more
doaj   +1 more source

Primary care spirometry* [PDF]

European Respiratory Journal, 2007
Primary care spirometry is a uniquely valuable tool in the evaluation of patients with respiratory symptoms, allowing the general practitioner to diagnose or exclude chronic obstructive pulmonary disease (COPD), sometimes to confirm asthma, to determine the efficacy of asthma treatment and to correctly stage patients with COPD.
Derom, E., Liistro, G., Buffels, J., Schermer, Tjard R.J., Lammers, E., Wouters, Emiel, Decramer, M., van Weel, Chris   +7 more
openaire   +3 more sources

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Digital diagnostics, biomarkers and therapeutics in an evolving healthcare system: From promise to practice

British Journal of Clinical Pharmacology, EarlyView.
Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop, Gertjan J. A. Driessen, Adam F. Cohen, Matthijs D. Kruizinga   +3 more
wiley   +1 more source

Comparison of respiratory muscle activities and cardiovascular function during different breathing types in healthy adults: Costal breathing, flow incentive spirometry, and volume incentive spirometry.

PLoS ONE
BackgroundVarious breathing exercises are used to enhance lung function. However, many patients have reported experiencing breathlessness and an increased work of breathing during their use, but evidence supporting this is limited.
Preeyaphorn Songsorn, Kanyapit Chummee, Chutima Yaanan, Anurak Banlueharn, Kornanong Yuenyongchaiwat, Chalearmpong Pinupong, Sasipa Buranapuntalug   +6 more
doaj   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source