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Results 81 to 90 of about 109,733 (324)

Ventilation inhomogeneity in patients with cystic fibrosis measured by electrical impedance tomography [PDF]

, 2012
Objective: The distribution of ventilation within the lung is inhomogeneous. We hypothesized that the degree of inhomogeneity in patients with cystic fibrosis (CF) differs from that in healthy subjects.
Fischer, Rainald +3 more
core +1 more source

Impaired Respiratory Function as an Auxiliary Marker for Disease Progression in Different Motor Subtypes of Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The mechanisms underlying respiratory function impairments in different motor subtypes of Parkinson's disease (PD) remain poorly understood. Objectives This study aims to elucidate the differences in respiratory function between the two main PD motor subtypes, tremor‐dominant (TD) and postural instability gait difficulty (PIGD), and
Zhen Li +10 more
wiley +1 more source

Small airway function in obese individuals with self-reported asthma

ERJ Open Research, 2020
Diagnosis of asthma in obese individuals frequently relies on clinical history, as airflow by spirometry may remain normal. This study hypothesised that obese subjects with self-reported asthma and normal spirometry will demonstrate distinct clinical ...
Beno W. Oppenheimer +5 more
doaj +1 more source

SPIROMETRY IN A PHYSIOTHERAPY DEPARTMENT

Australian Journal of Physiotherapy, 1975
Spirometry is used to provide information which will assist in determining the amount of pulmonary impairment. Tests can be quite elaborate and sophisticated, but physiotherapy departments in hospitals without a respiratory laboratory, can provide a good deal of information by using simple spirometry.
openaire +3 more sources

Operational Development and Launch of an Adaptive Platform Trial in Amyotrophic Lateral Sclerosis: Processes and Learnings From the First Four Regimens of the HEALEY ALS Platform Trial

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Platform trials present several advantages over traditional interventional clinical trials. Here, we provide a detailed description of the operational framework of the HEALEY ALS Platform Trial. Methods Platform‐level procedures for regulatory oversight, safety, and site management were developed prior to trial launch ...
Brittney A. Harkey +279 more
wiley +1 more source

Inspiratory Muscle Training in Adults With Cerebral Palsy: Long Term Effects: A Double‐Blind Randomized, Controlled Trial

Research in Nursing &Health, EarlyView.
ABSTRACT Respiratory disease is one of the main causes of morbidity and mortality in adults with cerebral palsy (CP). The main objective of the study was to investigate the maintenance over time of improvements in respiratory parameters achieved with inspiratory muscle training (IMT).
Carlos Martin‐Sanchez +4 more
wiley +1 more source

Noncommunicable Respiratory Disease and Air Pollution Exposure in Malawi (CAPS). A Cross-Sectional Study. [PDF]

, 2019
RationaleNoncommunicable respiratory diseases and exposure to air pollution are thought to be important contributors to morbidity and mortality in sub-Saharan African adults.ObjectivesWe set out to explore the prevalence and determinants of ...
Balmes, John +7 more
core

Healthcare professional’s guide to cardiopulmonary exercise testing [PDF]

, 2015
Cardiopulmonary exercise testing (CPEX) is a valuable clinical tool that has proven indications within the fields of cardiovascular, respiratory and pre-operative medical care.
Frenneaux, Michael P. +4 more
core +1 more source

Acute and Chronic Effects of Smoking on Inflammation Markers in Exhaled Breath Condensate in Current Smokers [PDF]

, 2010
Background: Long-term cigarette smoking is associated with pulmonary inflammation, but the acute effects of smoking have been less well studied. Analysis of the exhaled breath condensate (EBC) can provide noninvasive markers that might be indicative of ...
Bals, Robert +6 more
core +1 more source

Semi‐Mechanistic Population Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Dupilumab on Pre‐Bronchodilator Forced Expiratory Volume in 1 Second (FEV1) in Uncontrolled Moderate‐To‐Severe Asthma

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT In this study, we investigated the pharmacokinetic/pharmacodynamic (PK/PD) relationship of dupilumab as an add‐on therapy in the intent‐to‐treat (ITT) uncontrolled moderate‐to‐severe asthma population and identified the factors significantly contributing to variability in forced expiratory volume in 1 second; (FEV1).
Li Zhang +3 more
wiley +1 more source

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