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Injectable Estradiol Dosing Regimens in Transgender and Nonbinary Adults Listed as Male at Birth. [PDF]
Kanin M+6 more
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Refractory hypokalaemia and hypertension in pregnancy in a woman with renal artery stenosis. [PDF]
Phillips J+3 more
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The antihypertensive efficacy of a quadruple single-pill combination in patients with resistant hypertension: study protocol for a randomized, open-label, crossover trial. [PDF]
Yao Y+5 more
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Prescribing patterns for treatment of acne vulgaris: A retrospective chart review at an urban public and private hospital. [PDF]
Syder NC+5 more
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Polymorphism of Spironolactone
Journal of Pharmaceutical Sciences, 1991Single crystals of two polymorphic and four solvated crystalline forms of spironolactone (C24H32O4S) were obtained using different solvents. The morphology, symmetry, and crystallographic parameters were determined for all crystal forms except for the one obtained from methanol.
B. Legendre+4 more
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British Journal of Dermatology, 1988
A survey of 54 patients taking spironolactone for hirsutes or acne showed that side-effects occurred in 91%; in 80% of patients, these were related to the anti-androgenic mechanism of the drug (menstrual disturbances, and breast enlargement and tenderness).
Bronwyn R. Hughes, William J. Cunliffe
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A survey of 54 patients taking spironolactone for hirsutes or acne showed that side-effects occurred in 91%; in 80% of patients, these were related to the anti-androgenic mechanism of the drug (menstrual disturbances, and breast enlargement and tenderness).
Bronwyn R. Hughes, William J. Cunliffe
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The spironolactone renaissance
Expert Opinion on Investigational Drugs, 2001Until recently, spironolactone was considered only as an antagonist at the aldosterone receptors of the epithelial cells of the kidney and was used clinically in the treatment of hyperaldosteronism and, occasionally, as a K(+)-sparing diuretic. The spironolactone renaissance started with the experimental finding that spironolactone reversed aldosterone-
Doggrell, Sheila A., Brown, Lindsay
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Readministration of Spironolactone in the Spironolactone-Intolerant Patient
Allergy and Asthma Proceedings, 1986We report a successful practical protocol for readministration of spironolactone in a patient with cirrhosis and severe ascites whose initial exposure to spironolactone resulted in erythema multiforme. Because salt and water restriction and other diuretics were ineffective, readministration of spironolactone was considered appropriate.
Paul A. Greenberger, Harold P. Lazar
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Spironolactone for hypertension
Cochrane Database of Systematic Reviews, 2010Spironolactone is an aldosterone antagonist, considered fourth line therapy for hypertension in patients already treated with multiple medications.Primary: to determine the effect of spironolactone on patient mortality, morbidity, and to quantify the magnitude of blood pressure lowering effect of spironolactone monotherapy.Secondary: to determine the ...
Josh Batterink+3 more
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