Results 311 to 320 of about 59,693 (345)

Spironolactone

Neonatal Network, 1999
DIURETICS ARE COMMONLY USED IN the neonatal intensive care unit (NICU) to remove excess extracellular fluid secondary to various diseases, such as chronic lung disease (CLD) and congestive heart failure (CHF). Diuretics are among the most used of all medications across age groups.
openaire   +2 more sources

Spironolactone and Endocrine Dysfunction

Annals of Internal Medicine, 1976
Therapy with spironolactone is often associated with estrogenlike side-effects, including impotence and gynecomastia in men and menstrual irregularity in women. Several possible mechanisms by which spironolactone could cause these side-effects have been identified.
Julio C. Pita, Richard J. Santen, Raymond H. Menard, Addison A. Taylor, D. Lynn Loriaux   +4 more
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ALDOSTERONISM AND SPIRONOLACTONE

Annals of Internal Medicine, 1969
Excerpt To the Editor:I was very interested in the article entitled "Aldosteronism in Hypertension: The Response to Spironolactone" by Spark and Melby (Ann. Intern. Med. 69: 685, 1968).
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Spironolactone-Induced Agranulocytosis

Drug Intelligence & Clinical Pharmacy, 1987
Agranulocytosis associated with spironolactone administration is described in a 57-year-old man. Four days after initiation of spironolactone, leukocyte counts decreased from 8.2 to 2.3 × 109/L with 6% neutrophils. Spironolactone, domperidone, and prochlorperazine were discontinued.
Kabirudeen T. Jivraj, Tom Noseworthy, Erwin G. Friesen, Elsie Konopad, Allan Shustack, Richard Johnston   +5 more
openaire   +3 more sources

Use of spironolactone to treat acne in adolescent females

Pediatric dermatology, 2020
Studies assessing the utility of spironolactone for treating acne in adolescent females are lacking. Thus, we sought to examine spironolactone's role in treating this patient population.
E. Roberts, S. Nowsheen, D. Davis, J. L. Hand, M. Tollefson, D. Wetter   +5 more
semanticscholar   +1 more source

Spironolactone‐induced hepatitis

Australasian Journal of Dermatology, 2001
SUMMARYThere is widespread use of spironolactone in medical practice and the indications for its use well established and side effect profile well known. Herein, we present a case of drug‐induced hepatitis occurring in a 50‐year‐old woman using spironolactone for the treatment of androgenetic alopecia. Six weeks after commencement of spironolactone the
Keng-Ee Thai, Rodney Sinclair
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Spironolactone: A Re-Examination

DICP, 1990
A review of the aldosterone antagonist spironolactone is presented. It is effective both as monotherapy and in combination with other hypotensive agents in the control of both essential and hyperaldosterone-induced hypertension. It is useful as a diuretic in conditions such as cirrhosis and congestive heart failure, and is most commonly employed ...
Hilary A. Skluth, John G. Gums
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Spironolactone. II. Bioavailability

Clinical Pharmacology & Therapeutics, 1976
The bioavailability of commercial 25‐mg spironolactone tablets and a new tablet preparation containing 100 mg of the drug has been determined in 12 healthy male subjects. After a 200‐mg oral dose of the drug given in a solution of polyethylene glycol‐400, the peak plasma level of the dethioacetylated metabolite canrenone was 633 ± 154 ng Iml (mean ± SD)
B. J. Baltes, Aziz Karim, Allen Y. Chao, J. Zagarella, T. C. Hutsell   +4 more
openaire   +3 more sources

Treatment of acne with spironolactone: a retrospective review of 395 adult patients at Mayo Clinic, 2007–2017

Journal of the European Academy of Dermatology and Venereology, 2020
Few large studies have assessed spironolactone treatment of adult female acne.
E. Roberts, S. Nowsheen, Mark D. P. Davis, Marian T. McEvoy, C. C. Newman, J. C. S. Valinotti, G. Sciallis, Rochelle R. Torgerson, David A Wetter   +8 more
semanticscholar   +1 more source

Hydrochlorothiazide and spironolactone in hypertension

Clinical Pharmacology & Therapeutics, 1979
A double‐blind study of hydrochlorothiazide and spironolactone, alone and in combination, was conducted in 49 patients with mild‐to‐moderate essential hypertension after a 4‐wk placebo washout period. In the whole group mean arterial blood pressure fell to levels of ≤107 mm Hg or declined by more than 15 mm Hg in 78% of the patients after twelve weeks ...
Myron H. Weinberger, G Schrijver
openaire   +3 more sources