Results 81 to 90 of about 7,255,419 (253)

Progress in Disease-Syndrome-Integrated Mouse Models of Lung Cancer

Shiyan dongwu yu bijiao yixue
Lung cancer has the highest mortality rate among malignant tumors worldwide, posing a severe threat to human health. Traditional Chinese medicine (TCM) offers unique advantages in treating lung cancer, with disease-syndrome-integrated animal models ...
ZHAO Yulei, HAN Bingbing, WANG Xingxin, YANG Guangjian, WANG Yajie, TANG Xiaoyong   +5 more
doaj   +1 more source

Retinitis Pigmentosa Treatment with Western Medicine and Traditional Chinese Medicine Therapies

Journal of Ophthalmology, 2015
Current management of retinitis pigmentosa (RP) includes an attempt at slowing down the degenerative process through therapies that use either Western or traditional Chinese medicine (TCM).
Jian Xu, Qinghua Peng
doaj   +1 more source

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

, 2012
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Lech, Maciej, Günthner, Roman, Regina Gröbmayr, Römmele, Christoph, Heni Eka Susanti, Susanti, Heni Eka, Heni Susanti, Maciej Lech, Roman Günthner, Hans-Joachim Anders, Christoph Römmele, Gröbmayr, Regina, Anders, Hans-Joachim   +12 more
core   +1 more source

Nursing of a patient with morning diarrhea treated with ginger-isolated gourd moxibustion based on the theory of Kidney as the Gate of the Stomach (基于“肾为胃之关”运用隔姜葫芦灸技术治疗五更泻1例护理体会)

中西医结合护理
This article reported the Traditional Chinese Medicine (TCM) nursing of a patient with morning diarrhea due to spleen-kidney Yang deficiency. Based on the theory of Kidney as the Gate of the Stomach, ginger-isolated gourd moxibustion was applied to warm ...
LI Weiwei (李维维)
doaj   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Protein and cell therapy for lecithin-cholesterol acyltransferase (LCAT) deficiency [PDF]

, 2009
Lecithin-cholesterol acyltransferase (LCAT) is an enzyme principally secreted by the liver into the circulation where it esterifies cholesterol and plays a key role in high- density lipoprotein (HDL) metabolism. In familial and acquired (liver disease)
Low, J K, Low, J.K.
core  

Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease [PDF]

, 2011
Background and Aims:We analyzed iron deficiency and the therapeutic response following intravenous ferric carboxymaltose in a large single-center inflammatory bowel disease (IBD) cohort.
Brand, Stephan, Burkhard Göke, Breiteneicher, Simone, Göke, Burkhard, Ochsenkühn, Thomas, Fabian Schnitzler, Stephan Brand, Maria Weidinger, Thomas Ochsenkühn, Simone Breiteneicher, Beigel, Florian, Weidinger, Maria, Schnitzler, Fabian, Löhr, Beate, Seiderer, Julia, Laubender, Rüdiger P., Beate Löhr, Tillack, Cornelia, Cornelia Tillack, Florian Beigel, Julia Seiderer, Rüdiger P. Laubender   +21 more
core   +1 more source

Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells

Biological Research, 2019
Background Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom.
Xiaomin Wang, Peike Peng, Zhiqiang Pan, Zhaoqin Fang, Wenli Lu, Xiaomei Liu   +5 more
doaj   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source