Results 121 to 130 of about 51,961 (246)

Successful Endoscopic Sealing of Gastric Perforation With Tissue Adhesive Following Endoscopic Treatment for Gastric Fundal Variceal Bleeding: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Gastric perforation after endoscopic treatment of gastric fundal variceal bleeding is extremely rare. In carefully selected patients with early, small perforations and limited peritoneal contamination, endoscopic tissue adhesive injection combined with conservative management may provide a feasible nonsurgical rescue strategy.
Tianwen Liu   +6 more
wiley   +1 more source

Laparoscopic splenectomy in hematological diseases [PDF]

open access: yes, 2004
Idiopathic thrombocytopenic purpura (ITP) is the most common indication for elective splenectomy. The laparoscopic approach has been used over the past ten years. Aim: To report our experience with laparoscopic splenectomy.
Burdiles Pinto, Patricio   +3 more
core  

Laparoscopic hemi-splenectomy

open access: yes, 2018
Laparoscopic splenectomy is now established as a safe and feasible procedure. However, it remains associated with some short- and long-term postoperative complications, especially infectious complications. To our knowledge, this is the first report (with
Busch, Olivier R.   +5 more
core   +1 more source

A First‐in‐Japanese Phase 1, Double‐Blind, Placebo‐Controlled, Parallel‐Cohort Study of Sefaxersen, an Antisense Oligonucleotide Targeting Complement Factor B, in Healthy Participants

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 9, September 2026.
Abstract Increased activity in the complement alternative pathway (AP) plays a key role in diseases such as IgA nephropathy (IgAN). This first‐in‐Japanese double‐blind Phase 1 study investigated the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of sefaxersen (RO7434656), an antisense oligonucleotide targeting complement factor ...
Takakazu Sato   +3 more
wiley   +1 more source

Splenectomy in hematology. Current practice and new perspectives

open access: yesHaematologica, 1999
BACKGROUND AND OBJECTIVE: Progress and changes in the management of blood diseases, in surgery and in video technology stimulate a critical reappraisal of splenectomy in hematology.
U Baccarani   +5 more
doaj  

The State of Shared Decision‐Making in Immune Thrombocytopenia: A Narrative Review and Health Care Provider Perspective

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Advances in the treatment of immune thrombocytopenia (ITP) have broadened the landscape of treatment options for patients. Shared decision‐making, a collaborative process between a patient and their health care team, is encouraged for these patients. The ultimate goal of shared decision‐making is to personalize treatment to
Shivi Jain   +3 more
wiley   +1 more source

Clinical Heterogeneity of Refractory Ascites After Pediatric Liver Transplantation Modulates Allograft Rejection Risk

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Refractory ascites (RA) post‐pediatric LT is stratified into two subtypes: Type I (portal hypertension‐driven) and Type II (immune‐mediated). Type I is linked to low GRWR and hypersplenism, while Type II involves ABO incompatibility and early T‐cell activation (elevated sIL‐2R). Type II increases rejection risk (OR = 2.212).
Bingran Wang   +15 more
wiley   +1 more source

Phenotypic and Genotypic Landscape of Sitosterolemia in China: Including a Rare Case With Nephronophthisis

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study describes the first reported case of concurrent sitosterolemia (STSL) and nephronophthisis (NPHP). Additionally, we provide a systematic review of the clinical and genetic characteristics of Chinese STSL patients, representing the largest comprehensive cohort in China to date.
Dan Ding   +4 more
wiley   +1 more source

Endoscopic Treatment for Esophagogastric Variceal Bleeding in Patients With Acute‐on‐Chronic Liver Failure: An Observational Study

open access: yesPortal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 226-240, September 2026.
In patients with acute‐on‐chronic liver failure (ACLF), esophagogastric variceal bleeding (EGVB) represents a critical complication associated with high short‐term mortality. This study evaluated the efficacy of endoscopic treatment in this specific population and identified prognostic factors associated with 6‐week rebleeding and mortality.
Yanan Sun   +7 more
wiley   +1 more source

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