Results 131 to 140 of about 14,941 (204)

Circulating Growth Differentiation Factor 15 (GDF15) in Paediatric Disease: A Systematic Review

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Growth Differentiation Factor 15 (GDF15), a nonspecific inflammatory marker and member of the TGF‐β superfamily, has a well‐established role in both inflammation and metabolic modulation, but lacks a comprehensive paediatric literature review.
David W. Kronenberger   +3 more
wiley   +1 more source

Beyond Childhood: Adult and Adolescent Sickle Cell Disease and Outcomes in Northern Ghana

open access: yeseJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Background Adults and adolescents face different barriers to healthcare utilization compared to children. Objective To describe adult and adolescent sickle cell disease (SCD) and outcomes in northern Ghana. Methods This was a retrospective cohort study of SCD patients aged 13 years and above, admitted between January 1, 2021 and December 31 ...
Kwadwo Faka Gyan   +8 more
wiley   +1 more source

Systemic Inflammatory Diseases in Children With Sickle Cell Disease: A French Multicenter Observational Study on Diagnostic and Therapeutic Issues

open access: yesPediatric Blood &Cancer, Volume 72, Issue 4, April 2025.
ABSTRACT Background Systemic inflammatory diseases (SIDs) have been reported in patients with sickle cell disease (SCD), but clinical data in children are scarce. Objectives To identify clinical and laboratory features at diagnosis of SID in children with SCD and to describe their evolution.
Caroline Vinit   +19 more
wiley   +1 more source

Partial Splenectomy for Epithelial (Epidermoid) Splenic Cysts: Report of Two Cases

open access: yesJournal of Nepal Medical Association, 2013
Primary splenic cyst is a relatively rare disease, and the majority of cases are classified as epithelial (epidermoid) cysts. Two cases with epithelial splenic cysts are presented.
Gun Raj Paudel   +3 more
doaj  

Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1109-1120, April 2025.
Summary Germline variants in DDX41 (DDX41MT‐germline predisposition syndrome [GPS]) are associated with predisposition to haematological malignancies (HM), including lymphoid and myeloid neoplasms (MN). We retrospectively analysed the clinical and molecular features of 195 patients diagnosed and treated at Mayo Clinic with DDX41MT‐GPS.
Yael Kusne   +16 more
wiley   +1 more source

Non‐Transfusion‐Dependent Thalassemia: An Image Gallery Worth a Thousand Words

open access: yes
American Journal of Hematology, Volume 100, Issue 4, Page 687-694, April 2025.
Khaled M. Musallam   +7 more
wiley   +1 more source

Improving Guideline Development Processes: Integrating Evidence Estimation and Decision‐Analytical Frameworks

open access: yesJournal of Evaluation in Clinical Practice, Volume 31, Issue 3, April 2025.
ABSTRACT Rationale, Aims and Objectives Despite using state‐of‐the‐art methodologies like Grades of Recommendation, Assessment, Development and Evaluation (GRADE), current guideline development frameworks still rely heavily on panellists' intuitive integration of evidence related to the benefits and harms/burdens of health interventions.
Benjamin Djulbegovic   +3 more
wiley   +1 more source

Thoracic and abdominal diagnostic imaging findings in dogs diagnosed with immune‐mediated polyarthritis: 71 cases (2011‐2023)

open access: yesJournal of Small Animal Practice, Volume 66, Issue 4, Page 272-279, April 2025.
Objectives To describe thoracic and abdominal imaging findings in dogs with immune‐mediated polyarthritis and to evaluate their impact on the decision to commence immunosuppressive therapy. Materials and Methods Retrospective case series describing imaging findings in dogs with immune‐mediated polyarthritis across modalities, including thoracic ...
L. Atkinson   +4 more
wiley   +1 more source

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