Results 11 to 20 of about 105,203 (341)

Splenectomy Correlates With Increased Risk of Pyogenic Liver Abscess: A Nationwide Cohort Study in Taiwan

open access: yesJournal of Epidemiology, 2015
Objectives: Little is known about the risk of pyogenic liver abscess in patients with splenectomy. We explored the relationship between splenectomy and pyogenic liver abscess in Taiwan.
Shih-Wei Lai   +3 more
doaj   +2 more sources

Recommendations regarding splenectomy in hereditary hemolytic anemias

open access: yesHaematologica, 2017
Hereditary hemolytic anemias are a group of disorders with a variety of causes, including red cell membrane defects, red blood cell enzyme disorders, congenital dyserythropoietic anemias, thalassemia syndromes and hemoglobinopathies. As damaged red blood
Achille Iolascon   +21 more
doaj   +2 more sources

BACTERIAL INFECTIONS FOLLOWING SPLENECTOMY FOR MALIGNANT AND NONMALIGNANT HEMATOLOGIC DISEASES

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2015
Splenectomy, while often necessary in otherwise healthy patients after major trauma, find its primary indication for patients with an underlying malignant or nonmalignant hematologic diseases.
Giuseppe Leone, Eligio Pizzigallo
doaj   +2 more sources

Splenectomy for primary immune thrombocytopenia revisited in the era of thrombopoietin receptor agonists: New insights for an old treatment

open access: yesAmerican journal of hematology/oncology, 2021
Although splenectomy is still considered the most effective curative treatment for immune thrombocytopenia (ITP), its use has significantly declined in the last decade, especially since the approval of thrombopoietin receptor agonists (TPO‐RAs). The main
Arthur Mageau   +19 more
semanticscholar   +1 more source

Survival outcomes of laparoscopic versus open total gastrectomy with nodal dissection for gastric cancer in a high‐volume Japanese center: A propensity score‐matched analysis

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 53-62, January 2023., 2023
To compare the survival outcomes of laparoscopic total gastrectomy (LTG) with those of open total gastrectomy (OTG), 580 patients were enrolled and 1:1 propensity score matching was implemented to reduce selection bias. Five‐year overall survival was better in the LTG group, and there was no significant difference in overall survival according to ...
Takahiro Kinoshita   +3 more
wiley   +1 more source

Post-splenectomy Sepsis: A Review of the Literature

open access: yesCureus, 2020
The spleen is an intraperitoneal organ that performs vital hematological and immunological functions. It maintains both innate and adaptive immunity and protects the body from microbial infections.
Faryal Tahir, J. Ahmed, Farheen Malik
semanticscholar   +1 more source

Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 122-130, January 2023., 2023
Abstract Major options for second‐line therapy in adults with chronic immune thrombocytopenia (ITP) include splenectomy, rituximab, and thrombopoietin receptor agonists (TRAs). The American Society of Hematology guidelines recommend rituximab over splenectomy, TRAs over rituximab, and splenectomy or TRAs while noting a lack of evidence on the cost ...
George Goshua   +5 more
wiley   +1 more source

Splenomegaly in predicting the survival of patients with advanced primary liver cancer treated with immune checkpoint inhibitors

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4880-4888, December 2022., 2022
Kaplan–Meier analysis demonstrated that patients with splenomegaly had worse OS than those without splenomegaly. Abstract Background & aims Immune checkpoint inhibitors (ICIs) play an increasingly important role in the treatment of primary liver cancer (PLC). Some patients with PLC experience symptoms of splenomegaly.
Lu‐Shan Xiao   +9 more
wiley   +1 more source

Impact of spleen size and splenectomy on outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis: A retrospective analysis by the chronic malignancies working party on behalf of European society for blood and marrow transplantation (EBMT)

open access: yesAmerican journal of hematology/oncology, 2020
The role of spleen size and splenectomy for the prediction of post‐allogeneic hematopoietic stem cell transplant (allo‐HCT) outcome in myelofibrosis remains under debate.
N. Polverelli   +28 more
semanticscholar   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

open access: yesHepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang   +18 more
wiley   +1 more source

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