Results 61 to 70 of about 76,347 (227)
Is Splenectomy A Cause of Antiviral Treatment Failure in Hepatitis C Virus Infection? [PDF]
, 2001 Raymundo Paraná +2 more
openalex +1 more source
Management Strategies for Refractory Esophageal Varices
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.ABSTRACT Gaucher disease (GD) is a rare lysosomal storage disorder characterized by multisystemic involvement. With the advent of enzyme replacement therapy (ERT), patient survival has improved, revealing new long‐term complications. We report a case of a 4‐year‐old male with severe neurovisceral GD who developed protein‐losing enteropathy (PLE ...
Vincenza Gragnaniello +7 more
wiley +1 more source
Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia
British Journal of Clinical Pharmacology, Volume 91, Issue 12, Page 3537-3541, December 2025.Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas +7 more
wiley +1 more source
Clinical Case Reports, Volume 13, Issue 12, December 2025.Case‐based review illustrating successful nonoperative management of blunt Grade III pancreatic transection with ductal disruption in a hemodynamically stable patient, highlighting the role of early imaging, multidisciplinary decision‐making, and tailored conservative treatment.
Mehdi Didi +6 more
wiley +1 more source
The role of adrenocortical steroids in reversing established homograft rejection [PDF]
, 1964 Renal homotransplantation was performed in 8 dogs. Antirejection therapy with azathioprine (BW 57-322, Imuran) was given in doses of 2 to 7.5 mg. per kilogram per day.
Axtell, HK +4 more
core
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Sclerosing angiomatoid nodular transformation is a rare benign splenic lesion that mimics malignancy on imaging. Recognition of the spoke‐wheel pattern and progressive enhancement on CT/MRI may aid in preoperative diagnosis. Laparoscopic splenectomy remains useful for both diagnosis and treatment when malignancy cannot be excluded.
Misato Sawai +11 more
wiley +1 more source
Successful Treatment of Refractory IgA‐Mediated Autoimmune Hemolytic Anemia With Bortezomib
eJHaem, Volume 6, Issue 6, December 2025.ABSTRACT Introduction IgA‐mediated autoimmune hemolytic anemia (AIHA) is a rare condition associated with severe hemolysis and limited therapeutic response. Bortezomib, a proteasome inhibitor, targets plasma cells responsible for autoantibody production.
Silvia Neri +8 more
wiley +1 more source