Results 111 to 120 of about 92,257 (303)

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Isolated Splenic Vein Thrombosis: An Unusual Cause and Review of the Literature

Canadian Journal of Gastroenterology, 2004
Isolated obstruction (mainly due to thrombosis) of the splenic vein usually results in left-sided portal hypertension and isolated fundal varice formation. This syndrome is a rare cause of gastrointestinal bleeding. Pancreatic diseases are among the most
Seyfettin Köklü, Aydın Köksal, Ömer Yolcu, Gürsel Bayram, Zişan Sakaoğulları, Kemal Arda, Burhan Şahin   +6 more
doaj   +1 more source

Diagnostic Accuracy of Cytology in Canine Splenic Lesions [PDF]

, 2018
Cytological evaluation of splenic lesions is a routine preoperative diagnostic technique. However, few studies have evaluated the utility of diagnostic cytology in canine splenic diseases (Ballegeer et al., 2007; Christensen et al., 2009; Watson et al ...
Tecilla, Marco, Caniatti, Mario, Gambini, Matteo, Forlani, Annalisa, Roccabianca, Paola   +4 more
core   +2 more sources

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Organ-preserving treatment of splenomegaly in portal hypertension: clinical outcomes 12 months after partial embolization of the splenic artery

Український журнал клінічної хірургії
Objective. To evaluate the hematological effects and clinical efficacy of partial splenic artery embolization in the treatment of splenomegaly and hypersplenism in patients with portal hypertension caused by chronic liver diseases.
S. M. Kozlov, V. A. Kondratiuk
doaj   +1 more source

PREVALENCE OF SPLENIC DISEASES IN DOGS: A RETROSPECTIVE STUDY OF 81 CASES [PDF]

, 2019
Splenic masses have a higher incidence compared to diffuse splenic enlargement in canine patients and are mostly encountered in older dogs. For the present study we reviewed records of canine patients submitted to the Pathology Department (Faculty of ...
Andrei Ungur, Alexandra Biriș, Andrei Răzvan Codea, Raluca Vidrighinescu, Sofia Daradics, Roxana Cora, Ștefania Dandea, Vlad Luca, Mihai Negru, Anca Bărbos, Corina Toma   +10 more
core   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution

Canadian Journal of Infectious Diseases and Medical Microbiology, 2018
Background/Purpose. Splenic abscess is rare with potentially life-threatening evolution. The aim of this study is to review the clinical features, microbiological etiologies, treatment, and outcomes of patients with splenic abscess. Methods.
Mei-Chun Lee, Chun-Ming Lee
doaj   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source