Results 41 to 50 of about 2,252,550 (207)

Splenic Artery Aneurysm: A Retrospective Study of Management in Alexandria University [PDF]

Ain-Shams Journal of Surgery, 2015
Background: Splenic artery aneurysms (SAAs) are rare but are increasingly being diagnosed as incidental findings. They account for around 60% of visceral artery aneurysms and are the third most common intra-abdominal aneurysms after aortic and iliac ...
Naguib ElAskari, Sameh Mostafa, Ahmed Osmane   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Splenic infarction

, 1989
Splenic infarction is a recognized sequel of a number of diseases but, until recently, it has been difficult to verify. Employing the new imaging techniques, the spleen has become diagnostically more accessible and increase in the number of splenic ...
Roikjaer, O., Lorentzen, T.
core   +1 more source

The spleen in liver cirrhosis: revisiting an old enemy with novel targets

Journal of Translational Medicine, 2017
The spleen is a secondary lymphoid organ which can influence the progression of multiple diseases, notably liver cirrhosis. In chronic liver diseases, splenomegaly and hypersplenism can manifest following the development of portal hypertension.
Liang Li, Mubing Duan, Weisan Chen, An Jiang, Xiaoming Li, Jun Yang, Zongfang Li   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Standards of the Polish Ultrasound Society – update. Spleen examination

Journal of Ultrasonography, 2013
Ultrasound scan of the spleen is an integral part of the overall abdominal examination. Due to its anatomical position, physical examination of the spleen is frequently supplemented with an ultrasound which plays a special role in the differential ...
Joanna Walczyk, Maria Krystyna Walas
doaj  

Clinical analysis on comparison of outcomes between partial splenic artery embolization and splenectomy for management of grade II–III splenic injury in blunt trauma

European Journal of Medical Research
Background The spleen is also the largest lymphoid organ and has important immune and haematopoietic functions. Traumatic splenic rupture often results in haemorrhagic shock and is life-threatening.
Xiaolong Xu, Meng Lv, Cheng Wang, Jianfeng Mei   +3 more
doaj   +1 more source

Splenic lymphangiomas as a common indication for splenectomy: a case series with literature review

BMC Surgery, 2022
Background Splenic lymphangiomas (SL) are very rare benign cystic lesions found in pediatric population. Their occurrence in adults is exceptional. Splenectomy is the common management of splenic lesions for diagnostic and/or therapeutic purpose. Our aim
Boubacar Efared, Aïchatou Balaraba Abani Bako, Hama Younssa, Idrissa Boubacar, Aliou Zabeirou, Hamadou Halidou Koura, Habiba Salifou Boureima, Soumaila Amadou, Idrissa Seriba Coulibaly, James Didier Lassey, Hassan Nouhou   +10 more
doaj   +1 more source