Results 41 to 50 of about 92,257 (303)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Splenic function in childhood coeliac disease [PDF]
Gut, 1982 We measured splenic function using a simple, non-isotopic method in childhood coeliac disease. No patients were shown to have hyposplenism. This has important clinical and therapeutic implications.
G R, Corazza +4 more
openaire +2 more sources
Esplenectomia na criança: análise de 78 casos. [PDF]
, 2001 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis ...
Zizemer, Janaína Raquel
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Spontaneous rupture of the spleen as a result of primary splenic lymphoma [PDF]
, 2016 Publisher version availableSpontaneous rupture of the spleen is a true surgical emergency that requires immediate management to prevent rapid exsanguination.
Mohammed, Ahmed M.A. +2 more
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Spontaneous splenic rupture and multiple lung embolisms due to cytomegalovirus infection: a case report and review of the literature. [Elektronisk resurs] [PDF]
, 2014 A 53-year-old woman presented with a spontaneous splenic rupture. The splenic rupture was considered a complication of a primary cytomegalovirus (CMV) infection as well as multiple pulmonary embolisms.
Böttiger, Blenda, +3 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Laparoscopic, Endoscopic and Robotic Surgery, 2020 Endoscopic retrograde cholangiopancreatography (ERCP) is an invasive procedure, which is widely used in the management of pancreas and biliary tract diseases. It may induce complications, such as pancreatitis, bleeding, and perforation. Splenic injury is
Kan Wang +3 more
doaj +1 more source
Splenic Artery Aneurysm: A Retrospective Study of Management in Alexandria University [PDF]
Ain-Shams Journal of Surgery, 2015 Background: Splenic artery aneurysms (SAAs) are rare but are increasingly being diagnosed as incidental findings. They account for around 60% of visceral artery aneurysms and are the third most common intra-abdominal aneurysms after aortic and iliac ...
Naguib ElAskari +2 more
doaj +1 more source